Document Detail

Relationship of birth season to clinical features, family history, and obstetric complication in schizophrenia.
MedLine Citation:
PMID:  8888360     Owner:  NLM     Status:  MEDLINE    
Birth in late winter and spring has been consistently shown to be a risk factor of schizophrenia. The relationship of late winter/spring birth to clinical characteristics and other putative risk factors, such as family history and obstetric complications, may provide clues to etiology. Data relating to season of birth, clinical features, family history, and obstetric complications were analyzed for 192 patients with schizophrenia as defined by Research Diagnostic Criteria (including schizoaffective disorder). There was no significant association of season of birth with any of the psychopathological dimensions nor was there a significant association with obstetric variables or family history. However, winter-born schizophrenic patients who had a negative family history were more likely to have a history of obstetric complications. These findings suggest that obstetric complications associated with schizophrenia are perhaps the result of some seasonal risk factors important in those without a family history of the disorder.
D Dassa; P C Sham; J van Os; K Abel; P Jones; R M Murray
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Psychiatry research     Volume:  64     ISSN:  0165-1781     ISO Abbreviation:  Psychiatry Res     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1997-02-21     Completed Date:  1997-02-21     Revised Date:  2009-09-29    
Medline Journal Info:
Nlm Unique ID:  7911385     Medline TA:  Psychiatry Res     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  11-7     Citation Subset:  IM    
Département de Psychiatrie, C.H.U. Timone, Marseille, France.
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MeSH Terms
Infant, Newborn
Middle Aged
Obstetric Labor Complications / diagnosis*
Prenatal Exposure Delayed Effects*
Psychiatric Status Rating Scales
Risk Factors
Schizophrenia / diagnosis,  etiology*,  genetics
Schizophrenic Psychology
Grant Support
//Wellcome Trust

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