| Relationship between urea and ammonium excretion in the urine of very-low-birth-weight infants appropriate for gestational age. | |
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MedLine Citation:
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PMID: 2360909 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In 14 very-low-birth-weight infants appropriate for gestational age the serum concentrations of urea and the excretions of urea and ammonium in the urine were studied on the 10th, 21st, and 42nd day of postnatal life. All infants were fed with a human milk preparation (6 g human milk lyophilisate per 100 ml fresh human milk). The enteral feeding could be started on the first day of life so that protein intakes were not different on the three study days (2.94 vs. 2.98 vs 3.13 g/kg.d). The renal excretion of urea increased significantly from the 10th to the 42nd day of life (1.2 +/- 0.13 vs 2.1 +/- 0.24 mmol/kg.d) whereas the excretion of ammonium decreased during the same time (0.53 +/- 0.06 vs 0.29 +/- 0.05 mmol/kg.d). There was a significantly negative correlation between the excretion of urea and of ammonia on all study days. The weight gain was sufficient for the given protein intakes (18.9 +/- 3.4 g/kg.d). The results indicate a transient limited capacity of the urea synthesizing system in the liver of very-low-birth-weight infants during the first weeks of life which should be considered if metabolic responses to protein intake are studied and evaluated in these infants. |
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Authors:
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G Boehm; E Gedlu; D M Müller; K Beyreiss; N C Räihä |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Biomedica biochimica acta Volume: 49 ISSN: 0232-766X ISO Abbreviation: Biomed. Biochim. Acta Publication Date: 1990 |
Date Detail:
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Created Date: 1990-08-01 Completed Date: 1990-08-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8304435 Medline TA: Biomed Biochim Acta Country: GERMANY, EAST |
Other Details:
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Languages: eng Pagination: 69-74 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, Karl-Marx-University, Leipzig, GDR. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acid-Base Equilibrium Ammonia / urine* Food, Formulated Gestational Age Humans Infant, Low Birth Weight* Infant, Newborn Kidney / metabolism Metabolic Clearance Rate Milk Proteins Nitrogen / metabolism Urea / blood, metabolism, urine* Weight Gain |
| Chemical | |
Reg. No./Substance:
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0/Milk Proteins; 57-13-6/Urea; 7664-41-7/Ammonia; 7727-37-9/Nitrogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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