Document Detail


Relationship between tracheal air flow and induced changes in intrathoracic volume. A basis for calibration of pneumocardiogram.
MedLine Citation:
PMID:  3398247     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The volume of air moved into the trachea due to ventricular activity--a record of which is the pneumocardiogram (PNCG)--is always less than true stroke volume. A new method of investigating this relationship consists of inducing a known volume change (delta V in) within the thorax and measuring the volume of air (delta V out) recorded with a pneumotachograph connected to the trachea. The range of delta V in was from 4 ml to 36 ml. A linear relationship (mean r = 0.98, p less than 0.001) between delta V out and delta V in was observed in 19 anesthetized, intubated dogs: delta V out = (f) delta V in, where f = 0.53 +/- 0.09 (mean +/- SD). The coefficient, f, ranged from 0.40 to 0.71. These results demonstrate that although f is subject-dependent, delta V out reliably reflects changes in delta V in. It is suggested that the technique of inducing a known volume change within the thorax and measuring the volume of air recovered from the trachea could be used as a method for calibrating the pneumocardiogram to obtain stroke volume.
Authors:
J L Wessale; J D Bourland; L A Geddes
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Japanese heart journal     Volume:  29     ISSN:  0021-4868     ISO Abbreviation:  Jpn Heart J     Publication Date:  1988 Jan 
Date Detail:
Created Date:  1988-09-07     Completed Date:  1988-09-07     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0401175     Medline TA:  Jpn Heart J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  99-106     Citation Subset:  IM    
Affiliation:
Hillenbrand Biomed. Eng. Cntr., Purdue University, West Lafayette, IN 47907.
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MeSH Terms
Descriptor/Qualifier:
Airway Resistance
Animals
Calibration
Dogs
Esophagus / physiology
Heart Function Tests / instrumentation,  methods*
Regression Analysis
Respiration*
Stroke Volume
Thorax / physiology*
Trachea / physiology*
Grant Support
ID/Acronym/Agency:
HL22321/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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