| Relationship between tissue characterisations with 40 MHz intravascular ultrasound imaging and slow flow during coronary intervention. | |
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MedLine Citation:
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PMID: 21729836 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Aims: To evaluate the plaque characteristics that predispose to the slow flow phenomenon during percutaneous coronary intervention (PCI). The slow flow phenomenon is a serious complication of PCI and is associated with poor prognosis. It is difficult to predict this phenomenon from greyscale intravascular ultrasound (IVUS) data obtained before PCI. iMap™ is a new software package for assessing plaque composition from data obtained by 40 MHz IVUS imaging. Methods and results: Ninety-five consecutive patients underwent 40 MHz IVUS, including 33 with acute coronary syndrome. Plaque volume was calculated by IVUS and plaque components were detected by iMap software. Plaques were characterised as fibrotic, lipidic, necrotic, or calcified. Correlations among plaque characteristics and the slow flow phenomenon were analysed. Slow flow during PCI was observed in 11 patients (11.6%). Both the absolute volume and percentage of necrotic plaque were significantly higher in the slow flow group than the normal flow group (43.3±33.5 mm3 vs. 20.1±17.2 mm3, p=0.0004, 19.7±5.1% vs. 14.6±8.3%, p=0.047). Receiver-operating characteristic analysis showed that the necrotic plaque volume and necrotic plaque ratio were significantly better predictors of slow flow during PCI compared with total plaque volume. The cut-off value of necrotic plaque volume for predicting slow flow was 21.6 mm3 (sensitivity of 81.8% and specificity of 61.9%). Conclusions: Characterisation of plaque by IVUS with iMap analysis may predict slow flow during PCI. |
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Authors:
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Makoto Utsunomiya; Hisao Hara; Kaoru Sugi; Masato Nakamura |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology Volume: 7 ISSN: 1969-6213 ISO Abbreviation: EuroIntervention Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-07-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101251040 Medline TA: EuroIntervention Country: France |
Other Details:
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Languages: eng Pagination: 340-6 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular Medicine, Toho Ohashi Medical Center, Tokyo, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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