| Relationship between time-resolved and non-time-resolved Beer-Lambert law in turbid media. | |
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MedLine Citation:
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PMID: 9194125 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The time-resolved Beer-Lambert law proposed for oxygen monitoring using pulsed light was extended to the non-time-resolved case in a scattered medium such as living tissues with continuous illumination. The time-resolved Beer-Lambert law was valid for the phantom model and living tissues in the visible and near-infrared regions. The absolute concentration and oxygen saturation of haemoglobin in rat brain and thigh muscle could be determined. The temporal profile of rat brain was reproduced by Monte Carlo simulation. When the temporal profiles of rat brain under different oxygenation states were integrated with time, the absorbance difference was linearly related to changes in the absorption coefficient. When the simulated profiles were integrated, there was a linear relationship within the absorption coefficient which was predicted for fractional inspiratory oxygen concentration from 10 to 100% and, in the case beyond the range of the absorption coefficient, the deviation from linearity was slight. We concluded that an optical pathlength which is independent of changes in the absorption coefficient is a good approximation for near-infrared oxygen monitoring. |
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Authors:
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Y Nomura; O Hazeki; M Tamura |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Physics in medicine and biology Volume: 42 ISSN: 0031-9155 ISO Abbreviation: Phys Med Biol Publication Date: 1997 Jun |
Date Detail:
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Created Date: 1997-08-22 Completed Date: 1997-08-22 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1009-22 Citation Subset: IM |
Affiliation:
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Biophysics Division, Hokkaido University, Sapporo, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biophysical Phenomena Biophysics Brain Chemistry Hemoglobins / chemistry Infrared Rays Light Male Models, Biological* Monte Carlo Method Muscle, Skeletal / chemistry Optics and Photonics Oximetry / instrumentation, methods*, statistics & numerical data Oxygen / analysis Rats Rats, Wistar Spectrophotometry, Infrared |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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