| Relationship between spray adhesives and congenital malformations. | |
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MedLine Citation:
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PMID: 472845 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Evidence from clinical impressions and laboratory slides that spray adhesive products could have a potentially dangerous mutagenic or teratogenic effect was first reported in 1973. However, similar laboratory slides observed by others revealed no significant difference between chromosomal slides of malformed infants and those of normal children in households whose members were exposed to spray adhesives. Because of opposing opinions, a pilot epidemiologic study was initiated to investigate the association between the use of spray adhesives and congenital malformations. All congenital malformations reported on birth certificates from 1971 through 1974 in Oklahoma County, Oklahoma were used. A normal birth was selected as a matching control for each case. Complete and usable questionnaires regarding 112 malformed subjects and 116 controls, including 56 matched controls, were received. There was a statistical association between malformed subjects and household members using spray adhesives. There appears to be sufficient epidemiologic evidence to reopen the controversy with the appeal for further studies. |
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Authors:
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S L Silberg; D R Ransom; J A Lyon; P S Anderson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Southern medical journal Volume: 72 ISSN: 0038-4348 ISO Abbreviation: South. Med. J. Publication Date: 1979 Sep |
Date Detail:
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Created Date: 1979-10-26 Completed Date: 1979-10-26 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404522 Medline TA: South Med J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1170-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Drug-Induced
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etiology* Adhesives / adverse effects* Aerosols Humans Infant Oklahoma Statistics as Topic |
| Chemical | |
Reg. No./Substance:
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0/Adhesives; 0/Aerosols |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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