| Relationship between some humoral factors and left ventricular hypertrophy in essential hypertension. | |
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MedLine Citation:
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PMID: 9275376 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the relationship between certain humoral factors and left ventricular hypertrophy (LVH) in essential hypertension. PATIENTS AND METHODS: 62 essential hypertension (EH) patients (32 men, 30 women; mean age, 55 years) and 20 normotensive healthy subjects (10 men, 10 women: mean age, 52 years) were studied. EH patients were divided into LVH group and non-LVH group by echocardiography. After an overnight fast, blood samples were taken for the determination of parathyroid hormone (PTH), angiotensin II (ATII) and aldosterone (ALD) by radioimmunoassay. RESULTS: There was a significant difference in PTH. AT II and ALD between the EH group and control group. Furthermore, in LVH group PTH, ATII and ALD elevated significantly as compared with non-LVH group. In addition, we found that LVMI (left ventricular mass index) correlated with ATII (r = 0.342, P < 0.01) and ALD (r = 0.356, P < 0.01). There was a more significant correlation between LVMI and PTH (r = 0.422, P < 0.0025). CONCLUSIONS: Some humoral factors are important determinants of LV mass. Besides the reninangiotensin-aldosterone system, PTH might play an important role in cardiac hypertrophy. |
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Authors:
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Y Hui; Y Hao; X Chen; S Jing; Z Dai |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chinese medical journal Volume: 109 ISSN: 0366-6999 ISO Abbreviation: Chin. Med. J. Publication Date: 1996 Nov |
Date Detail:
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Created Date: 1997-09-23 Completed Date: 1997-09-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7513795 Medline TA: Chin Med J (Engl) Country: CHINA |
Other Details:
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Languages: eng Pagination: 885-7 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Medicine, Electric Power General Hospital, Beijing. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aldosterone
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blood Angiotensin II / blood Female Humans Hypertension / blood*, complications Hypertrophy, Left Ventricular / etiology* Male Middle Aged Parathyroid Hormone / blood* Renin-Angiotensin System* |
| Chemical | |
Reg. No./Substance:
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0/Parathyroid Hormone; 11128-99-7/Angiotensin II; 52-39-1/Aldosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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