Document Detail

Relationship between periventricular hemorrhage, leukomalacia and brainstem lesions in prematurely born infants.
MedLine Citation:
PMID:  2712235     Owner:  NLM     Status:  MEDLINE    
The brain pathology in very prematurely born infants with intraventricular hemorrhage (IVH) was studied particularly as to the severity and site of the complicated brain lesions responsible for the prognosis. A high frequency of leukomalacia, pontosubicular necrosis and/or olivocerebellar neuronal loss was found in the cases of IVH, and these non-hemorrhagic brain lesions showed an increasing frequency with the grade of IVH. However, there was marked reduction of IVH, periventricular leukomalacia and, in particular, brainstem lesions in prematurely born cases of sudden infant death. These IVH and associated conditions have different pathogenesis, but factors responsible for their occurrence may be present together in each case.
S Takashima; T Mito; S Houdou; Y Ando
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain & development     Volume:  11     ISSN:  0387-7604     ISO Abbreviation:  Brain Dev.     Publication Date:  1989  
Date Detail:
Created Date:  1989-06-08     Completed Date:  1989-06-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  121-4     Citation Subset:  IM    
Division of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, Tokyo, Japan.
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MeSH Terms
Abnormalities, Multiple / pathology*
Brain Stem / pathology*
Cerebral Hemorrhage / complications*,  pathology
Encephalomalacia / complications*
Infant, Newborn
Infant, Premature, Diseases / complications*,  pathology
Leukomalacia, Periventricular / complications*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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