Document Detail

Relationship between peri-intraventricular hemorrhage and neonatal hyperbilirubinemia in very low-birthweight infants.
MedLine Citation:
PMID:  3307797     Owner:  NLM     Status:  MEDLINE    
The incidence of hyperbilirubinemia (serum bilirubin values greater than 205 mumol/l) in two groups of preterm infants (birthweight less than 1500 gm) with and without peri-intraventricular hemorrhage (PIVH) was studied. In the first 10 days of life, 16 (39%) of the 41 infants with PIVH vs. 22 (46.8%) of those without PIVH (n = 47) had high bilirubin levels. No difference in peak serum bilirubin concentrations nor a need for phototherapy was noted between the two groups (P greater than 0.07). Forty-one infants had PIVH: 30 had PIVH grade I or II and 11 had grade III or IV. No statistically significant correlation was found between degree of PIVH and hyperbilirubinemia. Moreover, at 12 months corrected age, major and minor handicaps were equally distributed between the two groups. The neurologic outcome appeared to relate, in largest part, to the severity of the PIVH, and to not be influenced by the hyperbilirubinemia. We conclude that there is no positive relationship between incidence and extension of PIVH, plasma bilirubin levels, and outcome in very low-birth weight infants.
M Amato; J C Fauchere; G von Muralt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  4     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1987-11-16     Completed Date:  1987-11-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  275-8     Citation Subset:  IM    
Department of Perinatal Medicine, University of Berne, Switzerland.
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MeSH Terms
Brain Damage, Chronic / etiology
Cerebral Hemorrhage / complications*,  physiopathology
Follow-Up Studies
Infant, Low Birth Weight / growth & development*
Infant, Newborn
Jaundice, Neonatal / complications*,  physiopathology
Prospective Studies
Risk Factors

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