| Relationship between the percentage of predicted cardiorespiratory fitness and cardiovascular disease risk factors in premenopausal women: a MONET study. | |
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MedLine Citation:
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PMID: 20082604 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the relationships between the percentage predicted cardiorespiratory fitness (%CRF) and the anthropometric and metabolic cardiovascular disease risk factors in asymptomatic, premenopausal women. METHODS: Data are baseline values obtained in 97 healthy premenopausal women (age 49.9 +/- 1.9 years; body mass index 23.2 +/- 2.2 kg/m(2)) participating in a longitudinal study from 2004 to 2009. The outcome measures were peak oxygen consumption (VO(2) peak), body mass index, body composition (percentage fat, fat mass, fat-free mass), waist circumference, abdominal subcutaneous fat, visceral fat, resting blood pressure and fasting lipids, glucose and insulin levels. RESULTS: The %CRF was negatively associated with body mass index, fat mass, percentage fat, waist circumference, abdominal subcutaneous fat, visceral fat, triglycerides, triglyceride/high density lipoprotein cholesterol, total cholesterol, total cholesterol/high density lipoprotein cholesterol, fasting insulin levels and HOMA-IR (- 0.59 < or = r < or = - 0.20; 0.01 < p < 0.05) and positively associated with insulin sensitivity index (r = 0.23; p < 0.05). VO(2) peak was associated with the same variables; however, correlations were slightly better (- 0.70 < or = r < or = 0.30; 0.01 < p < 0.05). Stepwise multiple regression analysis showed that %CRF was only independently correlated with plasma triglyceride levels. CONCLUSION: The results of this study suggest that %CRF was not a major predictor of anthropometric and metabolic variables associated with an increased risk of cardiovascular disease in asymptomatic premenopausal women. Finally, the VO(2) peak is a better predictor than the %CRF to assess the risk of cardiovascular disease in asymptomatic premenopausal women. |
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Authors:
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J Abdulnour; P Boulay; M Brochu; R Rabasa-Lhoret; S Yasari; D Prud'homme |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Climacteric : the journal of the International Menopause Society Volume: 13 ISSN: 1473-0804 ISO Abbreviation: Climacteric Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-06-14 Completed Date: 2010-09-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9810959 Medline TA: Climacteric Country: England |
Other Details:
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Languages: eng Pagination: 347-54 Citation Subset: IM |
Affiliation:
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School of Human Kinetics, Faculty of Health Science, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Fat Blood Glucose / analysis Blood Pressure Body Composition Body Mass Index Cardiovascular Diseases / etiology* Exercise Test Female Glucose Tolerance Test Humans Insulin / blood Intra-Abdominal Fat Lipids / blood Longitudinal Studies Middle Aged Oxygen Consumption Physical Fitness / physiology* Premenopause / physiology* Risk Factors Waist Circumference |
| Grant Support | |
ID/Acronym/Agency:
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0602145.02//Canadian Institutes of Health Research |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Lipids; 11061-68-0/Insulin |
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