Document Detail

Relationship between oxidative stress in cord blood and route of delivery.
MedLine Citation:
PMID:  16113571     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate the effect of route of delivery on the antioxidant system of newborns. METHODS: We used the cord blood taken during labor of 56 vaginal deliveries and 50 elective cesarean sections. The specimens were analyzed for the plasma malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) and glucose 6-phosphate dehydrogenase (G6PD) activity and leukocyte count. RESULTS: SOD and CAT activities were significantly higher in the elective cesarean group than the vaginal delivery group (p < 0.01 and p < 0.005, respectively), but G6PD activity was similar between the groups. Plasma MDA level was lower in the cesarean group compared to the vaginal delivery group (p < 0.001). Leukocyte count was higher in the vaginal delivery group (p < 0.005). CONCLUSION: Our findings suggest that the route of delivery has an effect on oxidative stress in newborns exposed to oxidative stress during delivery. It can be suggested that the antioxidant system works more efficiently to overcome oxidative stress in newborns delivered via cesarean section.
Fatma Inanc; Metin Kilinc; Gurkan Kiran; Alanur Guven; Ergul Belge Kurutas; I Gurkan Cikim; Omer Akyol
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  20     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:    2005 Sep-Oct
Date Detail:
Created Date:  2005-08-22     Completed Date:  2005-12-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  450-3     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2005 S. Karger AG, Basel.
Department of Biochemistry, Medical Faculty, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antioxidants / metabolism
Catalase / blood
Cesarean Section*
Delivery, Obstetric / methods*
Fetal Blood / metabolism*
Glucosephosphate Dehydrogenase / blood
Infant, Newborn
Malondialdehyde / blood
Oxidative Stress / physiology*
Superoxide Dismutase / blood
Reg. No./Substance:
0/Antioxidants; 542-78-9/Malondialdehyde; EC Dehydrogenase; EC; EC Dismutase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Fetal hydrocephalus and intrauterine cerebral ventriculoscopy: an animal model.
Next Document:  Is conservative management of prenatal and neonatal ovarian cysts justifiable?