Document Detail


Relationship between oral tissue blood flow and oxygen tension in rabbit.
MedLine Citation:
PMID:  19815995     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Several studies have reported tissue blood flow and tissue oxygen tension during anesthesia, whereas there are few reports that discuss the relationship between tissue blood flow and tissue oxygen tension. The goal of this study was to investigate the relationship between these two variables before and after stellate ganglion block (SGB). We utilized 8 male Japan White rabbits. Anesthesia was maintained with propofol. For SGB, 0.2 ml of 1% lidocaine was injected and changes in mandibular bone marrow blood flow (BBF) and mandibular bone marrow oxygen tension (PbO(2)) were observed (Group B). After the observed variables completely recovered, 0.2 ml of 1% lidocaine was again injected and changes in masseter muscle blood flow (MBF) and masseter muscle oxygen tension (PmO(2)) were observed (Group M). The observed variables were hemodynamic parameters, common carotid artery blood flow, L (left side)-BBF, R (right side)-BBF, L-PbO(2), R-PbO(2), L-MBF, R-MBF, L-PmO(2) and R-PmO(2). In both groups, positive correlations (r=0.99; y=0.68x - 3.49 in Group B and r=0.99; y=0.62x + 0.47 in Group M) were observed when tissue blood flow was set at the X-axis and tissue oxygen tension at the Y-axis. In contrast, when tissue blood flow was set at the Y-axis and tissue oxygen tension at the X-axis, two regression lines almost overlapped (y=1.47x + 5.12 in Group B and y=1.59x - 0.28 in Group M). Therefore, it is estimated that tissue blood flow increases by approximately 15 ml/min/100g when tissue oxygen tension increases by 10 mmHg. In conclusion, there is a positive correlation between tissue blood flow and tissue oxygen tension. Changes in tissue oxygen tension should reflect the increase or decrease in tissue blood flow.
Authors:
Yui Terakawa; Tatsuya Ichinohe; Yuzuru Kaneko
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Bulletin of Tokyo Dental College     Volume:  50     ISSN:  0040-8891     ISO Abbreviation:  Bull. Tokyo Dent. Coll.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-10-09     Completed Date:  2009-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505414     Medline TA:  Bull Tokyo Dent Coll     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  83-90     Citation Subset:  D    
Affiliation:
Department of Dental Anesthesiology, Tokyo Dental College, Mihama-ku, Chiba, Japan. terakawayui@tdc.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Anesthetics, Intravenous / administration & dosage
Anesthetics, Local / administration & dosage
Animals
Bone Marrow / blood supply*
Carotid Artery, Common
Lidocaine / administration & dosage
Male
Mandible / blood supply
Masseter Muscle / blood supply*
Nerve Block / methods*
Oxygen / blood*,  physiology
Partial Pressure
Propofol / administration & dosage
Rabbits
Regional Blood Flow
Stellate Ganglion / drug effects
Chemical
Reg. No./Substance:
0/Anesthetics, Intravenous; 0/Anesthetics, Local; 137-58-6/Lidocaine; 2078-54-8/Propofol; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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