| Relationship between nonalcoholic fatty liver disease and metabolic syndrome. | |
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MedLine Citation:
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PMID: 21401898 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this study was to investigate the prevalence of nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) in subjects who underwent a routine health checkup. We intended to establish a clinical association between NAFLD and MS as well as to compare the diagnostic criteria of MS based on the definitions set forth by the International Diabetes Federation (IDF), the US National Cholesterol Education Program Adult Treatment Panel III (2001) (NCEP/ATP-III) and the Metabolic Syndrome Study Group of Chinese Diabetes Society (CDS). METHODS: Weight, height, waist circumference, hip circumference, percentage of body fat, blood pressure and ultrasound of liver were performed on subjects undergoing routine health checkup. Serum triglyceride, total cholesterol, high density lipoprotein cholesterol and fasting plasma glucose level were measured. RESULTS: A total of 2394 subjects were included in this analysis and 437 had NAFLD. The prevalence of MS in the whole sample according to IDF, NCEP/ATP-III and CDS definitions was 11.11%, 8.48% and 5.30%, respectively. The total degree of agreement between IDF, NCEP/ATP-III and CDS definition was 87.76%. The prevalence of MS in NAFLD subjects is much higher than that in non-NAFLD subjects. The prevalence of NAFLD in MS subjects is also much higher than that in non-MS subjects. CONCLUSION: The prevalence of MS varied depending on the diagnostic criteria used. NAFLD was strongly associated with the MS, although it remains unknown whether NAFLD is a cause or effect of MS. |
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Authors:
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Shao Hua Chen; Fan He; Hua Li Zhou; Hong Ru Wu; Chen Xia; You Ming Li |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of digestive diseases Volume: 12 ISSN: 1751-2980 ISO Abbreviation: J Dig Dis Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101302699 Medline TA: J Dig Dis Country: Australia |
Other Details:
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Languages: eng Pagination: 125-30 Citation Subset: IM |
Copyright Information:
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© 2011 The Authors. Journal of Digestive Diseases © 2011 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine and Blackwell Publishing Asia Pty Ltd. |
Affiliation:
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Department of Gastroenterology, The First Affiliated Hospital of College of Medicine, Zhejiang University Zhejiang Center for Disease Control and Prevention, Hangzhou, Zhejiang Province, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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