| Relationship between the neonatal white blood cell count and histologic chorioamnionitis in preterm newborns. | |
| | |
MedLine Citation:
|
PMID: 22813065 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Abstract Objective: The aim was to examine the relationship between neonatal WBC count and the diagnosis of histologic chorioamnionitis (HCA). Design: We measured WBC, a widely used marker of inflammation, to evaluate whether the values at birth were associated with HCA. Setting: NICU: Department of Pediatrics of Padua University, Padua (Italy) Subjects: WBC count was evaluated In 71 preterm neonates (<32 weeks of gestation) with HCA and in a control group without HCA on day 1, 3, and 6 after delivery. Logistic regression analysis and diagnostic accuracy analysis were used to assess the association between WBC counts and HCA. Main results: WBC levels were significantly higher in infants with HCA than in those without HCA (Median IQR, WBC (x10(9)/l): day 1, 13.2 (6.2-21.8) vs 8.1 (6-11.4), p< 0.001; day 3, 17.4 (11.4-26.9) vs 6.3 (5.2-8.3), p< 0.001; day 6, 18.4 (11.1-31) vs 6.5 (4.4-9), p< 0.0001). The neonatal WBC count on the third day of life was the most sensitive parameter associated with HCA (sensitivity, 0.80, specificity 0.88). The cut-off value based on the ROC curve was 10 (x10(9)/L). Conclusions: WBC count in the third day of life is strongly associated with HCA. |
| | |
Authors:
|
Vincenzo Zanardo; Carla Peruzzetto; Daniele Trevisanuto; Francesco Cavallin; Stefania Vedovato; Gianluca Straface; Silvia Chiarelli |
Related Documents
:
|
22893555 - Randomized controlled trial of vinyl bags versus thermal mattress to prevent hypothermi... 18847065 - Home births in the uk, 1955 to 2006. 22891185 - Health care utilization by preterm infants with respiratory complications in quebec. 17368665 - Factors influencing women's decision to have a home birth in rural turkey. 13106705 - The uses and predictive limitations of intelligence tests in infants and young children. 7640315 - Closure of patent ductus arteriosus decreases pulmonary myeloperoxidase in premature in... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-7-20 |
Journal Detail:
|
Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: - ISSN: 1476-4954 ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
|
Created Date: 2012-7-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Pediatrics, Policlinico Abano Terme, Abano Terme, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Tilted Face-Centered-Cubic Supercrystals of PbS Nanocubes.
Next Document: 'Slipping through the cracks': Policy implications of delays in HIV treatment seeking.