Document Detail

Relationship between manometric and videofluoroscopic measures of swallow function in healthy adults and patients treated for head and neck cancer with various modalities.
MedLine Citation:
PMID:  18956228     Owner:  NLM     Status:  MEDLINE    
Pharyngeal manometry complements the modified barium swallow with videofluoroscopy (VFS) in diagnosing pressure-related causes of dysphagia. When manometric analysis is not feasible, it would be ideal if pressure information about the swallow could be inferred accurately from the VFS evaluation. Swallowing function was examined using VFS and concurrent manometry in 18 subjects (11 head and neck patients treated with various modalities and 7 healthy adults). Nonparametric univariate and multivariate analyses revealed significant relationships between manometric and fluoroscopic variables. Increases in pressure wave amplitude were significantly correlated with increased duration of tongue base to pharyngeal wall contact, reduced bolus transit times, and oropharyngeal residue. Pharyngeal residue was the most important VFS variable in reflecting pharyngeal pressure measurements. Certain VFS measures were significantly correlated with measures of pressure assessed with manometry. Further research is needed before observations and measures from VFS alone may be deemed sufficient for determining pressure-generation difficulties during the swallow in patients who are unable or unwilling to submit to manometric testing.
Barbara Roa Pauloski; Alfred W Rademaker; Cathy Lazarus; Guy Boeckxstaens; Peter J Kahrilas; Jerilyn A Logemann
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2008-10-28
Journal Detail:
Title:  Dysphagia     Volume:  24     ISSN:  1432-0460     ISO Abbreviation:  Dysphagia     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-27     Completed Date:  2010-09-29     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  8610856     Medline TA:  Dysphagia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  196-203     Citation Subset:  IM    
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MeSH Terms
Case-Control Studies
Deglutition Disorders / diagnosis*,  etiology
Fluoroscopy / instrumentation
Head and Neck Neoplasms / complications*
Manometry / instrumentation*
Middle Aged
Multivariate Analysis
Statistics as Topic
Video Recording / instrumentation
Grant Support
P01 CA040007/CA/NCI NIH HHS; P01 CA040007-14/CA/NCI NIH HHS; P01CA40007/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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