Document Detail

Relationship between low blood pressure and depressive symptomatology in older people.
MedLine Citation:
PMID:  10733049     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To determine if low blood pressure is associated with a definable constellation of somatic and psychological symptoms in older persons. DESIGN: A population-based study. SETTING: In-home interviews in five southwestern states. PARTICIPANTS: A total of 2723 Mexican Americans aged 65 or older not living in institutions. MEASURES: Blood pressure, Center for Epidemiologic Studies Depression Scale (CES-D), global self-rating of health, and self-esteem. RESULTS: Bivariate analyses indicate a significant relationship between low blood pressure and increased depressive symptomatology; for example, systolic hypotensive subjects scored a CES-D mean of 12.07 +/- .67 compared to 8.99 +/- .95 for normotensives (P < .01). Regression analyses supported these findings when controlling for confounders such as gender, age, and use of antihypertensive medications. Subjects with low blood pressure also scored lower on self-esteem and global self-reported health and reported more days waking up feeling tired. CONCLUSIONS: These data support the existence of a relationship between low blood pressure and higher levels of depressive symptomatology as well as a constellation of somatic and psychosocial symptoms.
C A Stroup-Benham; K S Markides; S A Black; J S Goodwin
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the American Geriatrics Society     Volume:  48     ISSN:  0002-8614     ISO Abbreviation:  J Am Geriatr Soc     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-04-04     Completed Date:  2000-04-04     Revised Date:  2008-03-10    
Medline Journal Info:
Nlm Unique ID:  7503062     Medline TA:  J Am Geriatr Soc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  250-5     Citation Subset:  IM    
Center on Aging, and Department of Medicine, University of Texas Medical Branch, Galveston 77555-0664, USA.
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MeSH Terms
Aged, 80 and over
Aging / physiology
Antihypertensive Agents / therapeutic use
Depression / diagnosis,  ethnology*,  etiology*
Hypotension / complications*,  ethnology*
Interviews as Topic
Mexican Americans* / statistics & numerical data
Multivariate Analysis
Regression Analysis
Southwestern United States / epidemiology
Grant Support
R01 AG10939-04/AG/NIA NIH HHS
Reg. No./Substance:
0/Antihypertensive Agents
Comment In:
J Am Geriatr Soc. 2000 Mar;48(3):336-7   [PMID:  10733064 ]

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