Document Detail


Relationship between lesion vessel area and myocardial salvage assessed by myocardial single photon emission computed tomography in acute myocardial infarction with stenting after thrombectomy.
MedLine Citation:
PMID:  16570534     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To study the relationship between lesion vessel area and myocardial salvage assessed by myocardial single photon emission computed tomography (SPECT) in acute myocardial infarction with stenting after thrombectomy. METHODS: This study included 71 patients who underwent stenting after thrombectomy for acute myocardial infarction. Intravascular ultrasound (IVUS) was performed after thrombectomy. Patients were classified into two groups: the High group with external elastic membrane cross-sectional area (EEM-CSA) of the lesion > or = 18 mm2 (34 patients) and the Low group with EEM-CSA < 18 mm2 (37 patients). Dual isotope myocardial SPECT imaging was undertaken by perfusion SPECT (201Tl or 99mTc-MIBI) and 123I-15-(p-iodophenyl)-3-(R,-S)-methylpentadecanoic acid (BMIPP). The image of the left ventricular myocardium was divided into 17 segments to calculate total defect score using a 5-grade assessment (0: normal-4: defect). Differences in total defect score of perfusion SPECT and 123I-BMIPP was defined as mismatch. RESULTS: Culprit lesion morphology was assessed by IVUS. A higher incidence of lipid pool-like images (47% vs 5%, p < 0.01) was observed in the High group. The results of myocardial SPECT study revealed no difference in the total defect score of 123I-BMIPP (18.3 +/- 5.5 vs 17.3 +/- 6.3 points) but the mismatch in total defect score of perfusion SPECT and 123I-BMIPP was significantly lower in the High group (3.8 +/- 3.9 vs 7.7 +/- 4.2 points, p < 0.05). CONCLUSIONS: Patients with a high culprit lesion vessel area show fewer beneficial effects in myocardial salvage compared with those with low vessel area as assessed by myocardial SPECT in acute myocardial infarction with stenting after thrombectomy.
Authors:
Masatsugu Nakano; Kenji Wagatsuma; Hideyuki Sato; Hideo Nii; Hideo Amano; Mikihito Toda; Shohei Yamashina; Junichi Yamazaki
Related Documents :
15682844 - Scatter and cross-talk correction for one-day acquisition of 123i-bmipp and 99mtc-tetro...
9363744 - Indium-111 antimyosin scintigraphy before and after coronary bypass surgery: unexpected...
8569594 - 201tl reinjection and late redistribution in the detection of viable myocardium.
9553164 - Technetium-99m q4: a prototype cationic perfusion radiotracer with myocardial washout.
15647364 - Atp flux through creatine kinase in the normal, stressed, and failing human heart.
16784914 - Effect of atherosclerotic regression on total luminal size of coronary arteries as dete...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiology     Volume:  47     ISSN:  0914-5087     ISO Abbreviation:  J Cardiol     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-03-30     Completed Date:  2006-05-03     Revised Date:  2006-05-06    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  123-31     Citation Subset:  IM    
Affiliation:
Division of Interventional Cardiology, Toho University Omori Medical Center, Omori-nishi 6-11-1, Ota-ku, Tokyo 143-8541. toho9686@lily.ocn.ne.jp
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Coronary Vessels / pathology*,  ultrasonography
Fatty Acids / diagnostic use
Female
Humans
Iodobenzenes / diagnostic use
Male
Middle Aged
Myocardial Infarction / radionuclide imaging*,  surgery
Stents*
Thrombectomy*
Tomography, Emission-Computed, Single-Photon*
Ultrasonography, Interventional
Chemical
Reg. No./Substance:
0/Fatty Acids; 0/Iodobenzenes; 116754-87-1/iodofiltic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of collateral circulation on myocardial protection in patients with acute myocardial infarcti...
Next Document:  Method analysis for optimal continuous imaging using intravascular optical coherence tomography.