Document Detail


Relationship between left ventricular geometric pattern and systolic and diastolic function in treated Nigerian hypertensives.
MedLine Citation:
PMID:  20224841     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Despite a high worldwide prevalence of left ventricular hypertrophy among black patients, the association of a specific left ventricular geometric pattern with left ventricular dysfunction is rare. The aim of this study was to explore the possibility of such an association in Nigerian hypertensives. METHODS: This was a retrospective study consisting of 188 treated hypertensives. Echocardiography was used to allocate the patients to the following four groups: normal geometric pattern, concentric remodelling, eccentric hypertrophy and concentric hypertrophy. RESULTS: The mean age of the study population was 55.95 +/- 10.71 years. There were 75 females (39.9%). Concentric hypertrophy occurred in 72 (38.3%) patients and concentric remodelling in 53 (28.2%). Only 30 (16%) had a normal left ventricular geometric pattern. Hypertensive subjects with eccentric hypertrophy had the lowest ejection fraction, fractional fibre shortening and left ventricular ejection time but these did not reach statistical significance. The mean left atrial dimension was highest in the subjects with eccentric hypertrophy. CONCLUSION: In this study population of treated Nigerian hypertensives, concentric remodelling and hypertrophy were the predominant left ventricular geometrical patterns.
Authors:
Adeseye A Akintunde; Oluranti B Familoni; Patience O Akinwusi; O George Opadijo
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular journal of Africa     Volume:  21     ISSN:  1995-1892     ISO Abbreviation:  Cardiovasc J Afr     Publication Date:    2010 Jan-Feb
Date Detail:
Created Date:  2010-03-12     Completed Date:  2010-04-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101313864     Medline TA:  Cardiovasc J Afr     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  21-5     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Lautech Teaching Hospital, Osogbo, Osun State, Nigeria. iakintunde2@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
African Continental Ancestry Group
Aged
Antihypertensive Agents / therapeutic use*
Blood Pressure / drug effects*
Diastole
Female
Humans
Hypertension / complications,  drug therapy*,  ethnology,  physiopathology,  ultrasonography
Hypertrophy, Left Ventricular / ethnology,  etiology*,  physiopathology,  ultrasonography
Male
Middle Aged
Nigeria / epidemiology
Prevalence
Retrospective Studies
Stroke Volume
Systole
Treatment Outcome
Ventricular Dysfunction, Left / ethnology,  etiology*,  physiopathology,  ultrasonography
Ventricular Function, Left*
Ventricular Remodeling
Chemical
Reg. No./Substance:
0/Antihypertensive Agents

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