Document Detail

Relationship between juxtaglomerular apparatus and plasma renin activity in human reno-vascular hypertension.
MedLine Citation:
PMID:  917169     Owner:  NLM     Status:  MEDLINE    
Juxtaglomerular cell count (JGCC) and juxtaglomerular activity (JA) on the fragments of the ischemic kidney and plasma renin activity (PRA) in peripheral venous blood were studied in 26 renovascular patients. In 11 cases PRA was also measured in renal venous blood. JGCC and JA values were always above normal range and both were significantly related to the PRA values in peripheral venous blood, while only JA was related to the PRA values in renal venous blood. These data indicate that in human renovascular hypertension the juxtaglomerular apparatus is hyperplastic and hypergranulated: the correlation between its morphological appearance and PRA seems to indicate that the renin-angiotensin system may be in some way involved in the genesis of hypertension.
G Maltinti; F Arzilli; R Cortese; R Pedrinelli; L Poli; P Sassano; A Salvetti
Related Documents :
167999 - Disappearance of bradykinin in the renal circulation of dogs. effects of kininase inhib...
4693649 - Effect of intraluminal flow on proximal tubular reabsorption.
11753089 - Renal blood flow autoregulation in blood pressure control.
12511539 - Phase-contrast magnetic resonance flow quantification in renal arteries: comparison wit...
6331069 - Calcium antagonist verapamil inhibits adenosine-induced renal vasoconstriction in the dog.
9088869 - Renal effect of ym435, a new dopamine d1 receptor agonist, in anesthetized dogs.
6723779 - Comparative response of the heart and coronary vasculature to catecholamines, aminophyl...
6705189 - Increase of intraerythrocytic fructose-1,6-diphosphate after incubation of whole human ...
23193049 - Immuno-localization of type-iv collagen in the blood-gas barrier and the epithelial-epi...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nephron     Volume:  19     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1977  
Date Detail:
Created Date:  1977-12-29     Completed Date:  1977-12-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  220-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cell Count
Hypertension, Renal / enzymology*,  etiology,  pathology
Juxtaglomerular Apparatus* / cytology,  pathology
Kidney / enzymology
Middle Aged
Renin / blood*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Removal of guanidinosuccinic acid by hemodialysis.
Next Document:  Renal venous plasma renin reactivity in clinical and experimental renovascular hypertension: renin r...