| Relationship between interpregnancy interval and birth defects in Washington State. | |
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MedLine Citation:
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PMID: 21546941 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective:Interpregnancy interval (IPI) influences numerous adverse perinatal outcomes. IPI's impact on birth defects is unclear.Study Design:We conducted a population-based case-control study, using 1998 to 2008 administrative data from Washington State. A total of 10 772 cases, women whose second of two births resulted in an infant with a birth defect, were compared with 32 310 controls, women whose second of two births did not result in an infant with a birth defect.Result:Compared with mothers with an IPI between 18 to 23 months, those with an IPI <6 months or 60 months had elevated risks of delivering an infant with a birth defect (odds ratio=1.15, 95% confidence interval: 1.03 to 1.28, and odds ratio=1.15, 95% confidence interval: 1.04 to 1.26, respectively).Conclusion:We observed a J-shaped relationship between IPI and risk of having an infant with a birth defect. As this is one of the first studies to evaluate this association, confirmatory studies are needed.Journal of Perinatology advance online publication, 5 May 2011; doi:10.1038/jp.2011.49. |
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Authors:
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S Kwon; M Lazo-Escalante; M V Villaran; C I Li |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-05 |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: - ISSN: 1476-5543 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Surgery, University of Washington, Seattle, WA, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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