Document Detail

Relationship between hair elements and severity of atrioventricular block in horses.
MedLine Citation:
PMID:  17625246     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to investigate the relationships between the mean concentrations of trace elements and the severity of the second-degree atrioventricular (AV) block in the mane hair of horses. Electrocardiographs of horses were continually recorded for 6 h using a holter cardiac monitor to determine dropped ventricular beats (DVBs) which can be used as an indicator of the severity of the AV block. Mane hair Ca, Cu, Mg, and Zn concentrations were measured by the particle-induced X-ray emission method. The Zn/Cu ratio and Ca concentration in mane hair were significantly and positively correlated with the hourly DVBs in horse with a second-degree AV block (p<0.01, r2=0.485; p<0.05, r2=0.351, respectively). Proposed diagnostic cutoff points for hair Ca concentration and Zn/Cu ratio based on receiver operating characteristics curves analysis in detecting second-degree AV block were set at 1536 microg/g and 26.0, respectively. Those results with horse hair suggest that the evaluation of the Ca, Cu, Mg, and Zn status in mane hair by this method is strongly related to the severity of second-degree AV block and might predict the susceptibility of an individual much before the development of the symptom.
Kazuyuki Suzuki; Yoshiki Yamaya; Kimi Asano; Momoko Chiba; Kouichiro Sera; Tsutomu Matsumoto; Takeo Sakai; Ryuji Asano
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biological trace element research     Volume:  115     ISSN:  0163-4984     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-07-12     Completed Date:  2007-08-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  255-64     Citation Subset:  IM    
Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-8510, Japan.
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MeSH Terms
Calcium / metabolism
Copper / analysis
Hair / metabolism
Heart Block / diagnosis*,  pathology
ROC Curve
Regression Analysis
Trace Elements / analysis*
Zinc / analysis
Reg. No./Substance:
0/Trace Elements; 7440-50-8/Copper; 7440-66-6/Zinc; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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