Document Detail

Relationship between guideline treatment and health-related quality of life in asthma.
MedLine Citation:
PMID:  15176686     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to compare the health-related quality of life (HRQL) of asthma patients treated according to the 1997 National Institute of Health (NIH) international asthma guideline and that of asthmatics receiving non-guideline treatment. The suitability of 146 asthmatics' medication regimes was determined according to the 1997 NIH asthma guideline. Quality of life was assessed on a seven-point scale using the Asthma Quality of Life questionnaire. Just over half of the patients were not currently using the treatment considered necessary for controlling their asthma. Patients treated according to the guideline (n=72) had a significantly higher overall HRQL than patients with non-guideline treatment (5.7 versus 5.3). The differences were also significant for the subscales measuring symptoms and environmental exposure, but not for activities or emotional function. An association between non-guideline treatment and a poorer health-related quality of life in asthma patients treated in general practice was observed. This study supports the role of evidence-based guidelines in daily practice. Further studies are needed to determine if guideline treatment is responsible for the increase in health-related quality of life observed in this work.
L G Pont; T van der Molen; P Denig; G T van der Werf; F M Haaijer-Ruskamp
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The European respiratory journal     Volume:  23     ISSN:  0903-1936     ISO Abbreviation:  Eur. Respir. J.     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-06-04     Completed Date:  2004-08-17     Revised Date:  2013-05-23    
Medline Journal Info:
Nlm Unique ID:  8803460     Medline TA:  Eur Respir J     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  718-22     Citation Subset:  IM    
Dept of Clinical Pharmacology, Groningen University Institute of Drug Exploration, the Netherlands.
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MeSH Terms
Anti-Asthmatic Agents / therapeutic use*
Asthma / drug therapy*,  physiopathology*
Middle Aged
National Institutes of Health (U.S.)*
Practice Guidelines as Topic / standards*
Quality of Life*
Treatment Outcome
United States
Reg. No./Substance:
0/Anti-Asthmatic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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