Document Detail

Relationship between globus sensation and esophageal clearance.
MedLine Citation:
PMID:  19449225     Owner:  NLM     Status:  MEDLINE    
CONCLUSIONS: Videofluoroscopy (VF) in the prone position can diagnose a range of esophageal pathologies in all age groups. These correlate with globus sensation in younger and middle-aged patients in prone and supine positions. Abnormal esophageal clearance appears to be associated with globus sensation in young and middle-aged persons, but not in the elderly. OBJECTIVES: To assess the correlation between globus sensation and abnormal esophageal clearance by VF in relation to body position and to investigate age-related abnormal esophageal clearance, as well as to confirm the utility of VF in diagnosing globus sensation in patients. SUBJECTS AND METHODS: This was a prospective study. In 72 patients with globus sensation and 33 controls, esophageal clearance was assessed by VF in the upright, supine, and prone positions, and transfer of barium through the esophagus was classified as normal, esophageal retention, esophageal reflux, or pharyngeal reflux. The detection rate of abnormal esophageal clearance was compared among all subjects by age. RESULTS: In the upright position, VF detected no significant differences in the detection rate of abnormal esophageal clearance and reflux between the patients with globus sensation and controls; however, the detection rate of abnormal esophageal clearance was significantly higher in the prone than in the upright and supine positions (p<0.001), and in all positions was significantly higher among globus sensation patients (p<0.05). In the supine and prone positions, there were significantly higher detection rates of abnormal esophageal clearance in patients than in controls in the young group (p<0.05). Additionally in the prone position, there was a significantly higher detection rate of abnormal esophageal clearance and reflux in patients than in controls in the middle-aged group (p<0.05). In all positions, no significant differences were observed in the detection rate of abnormal esophageal clearance and reflux in the patients and controls in the elderly group.
Jin Adachi; Yukio Ohmae; Takehiro Karaho; Tetsuya Tanabe; Daisuke Mizokami; Kouji Hirota; Masayuki Tomifuji; Akihiro Kurita; Takeshi Matsunobu; Akihiro Shiotani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  130     ISSN:  1651-2251     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-06-14     Completed Date:  2010-10-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  England    
Other Details:
Languages:  eng     Pagination:  138-44     Citation Subset:  IM    
Department of Otolaryngology, National Defense Medical College, Tokorozawa, Japan.
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MeSH Terms
Age Factors
Aged, 80 and over
Barium Sulfate / diagnostic use
Contrast Media
Conversion Disorder / diagnosis*,  physiopathology
Esophageal Motility Disorders / diagnosis*,  physiopathology
Fluoroscopy / instrumentation*
Gastroesophageal Reflux / diagnosis,  physiopathology
Middle Aged
Prone Position
Prospective Studies
Reference Values
Regurgitation, Gastric / diagnosis,  physiopathology
Supine Position
Video Recording / instrumentation*
Reg. No./Substance:
0/Contrast Media; 7727-43-7/Barium Sulfate

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