| Relationship between germination of Candida albicans and increased adherence to human buccal epithelial cells. | |
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MedLine Citation:
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PMID: 6995309 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A strong correlation was shown between germination and increased adherence of Candida albicans to human buccal epithelial cells, indicating that germination or other changes in the fungi accompanying germination were responsible for enhanced adherence. Partial inhibition of germination by cysteine resulted in a comparably lower adherence. Preferential adherence of germinated fungi occurred in competition assays with nongerminated and germinated fungi. The enhanced adherence to human mucosal cells of germinated C albicans could represent one mechanism contributing to the pathogenicity of the organism. |
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Authors:
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L H Kimura; N N Pearsall |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Infection and immunity Volume: 28 ISSN: 0019-9567 ISO Abbreviation: Infect. Immun. Publication Date: 1980 May |
Date Detail:
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Created Date: 1980-10-21 Completed Date: 1980-10-21 Revised Date: 2010-09-13 |
Medline Journal Info:
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Nlm Unique ID: 0246127 Medline TA: Infect Immun Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 464-8 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Candida albicans
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physiology* Cheek Epithelial Cells Humans Mouth Mucosa / microbiology* Spores, Fungal |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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