Document Detail


Relationship between germination of Candida albicans and increased adherence to human buccal epithelial cells.
MedLine Citation:
PMID:  6995309     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A strong correlation was shown between germination and increased adherence of Candida albicans to human buccal epithelial cells, indicating that germination or other changes in the fungi accompanying germination were responsible for enhanced adherence. Partial inhibition of germination by cysteine resulted in a comparably lower adherence. Preferential adherence of germinated fungi occurred in competition assays with nongerminated and germinated fungi. The enhanced adherence to human mucosal cells of germinated C albicans could represent one mechanism contributing to the pathogenicity of the organism.
Authors:
L H Kimura; N N Pearsall
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Infection and immunity     Volume:  28     ISSN:  0019-9567     ISO Abbreviation:  Infect. Immun.     Publication Date:  1980 May 
Date Detail:
Created Date:  1980-10-21     Completed Date:  1980-10-21     Revised Date:  2010-09-13    
Medline Journal Info:
Nlm Unique ID:  0246127     Medline TA:  Infect Immun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  464-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Candida albicans / physiology*
Cheek
Epithelial Cells
Humans
Mouth Mucosa / microbiology*
Spores, Fungal
Comments/Corrections

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