| Relationship between free-radical lipid oxidation and efficiency of coronary angioplasty in coronary patients. | |
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MedLine Citation:
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PMID: 18683490 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Low-dose (250 mg daily) oral probucol produces a significant antioxidant effect in coronary patients: increases activity of glutathione peroxidase (enzyme utilizing lipoperoxides) and reduces the content of free-radical oxidation products in the blood. Probucol therapy for 7 days before and for 6 months after coronary angioplasty significantly reduces the severity of coronary artery stenosis. |
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Authors:
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A I Kaminnyi; V Z Lankin; E I Perepelitsa; G G Konovalova; A N Samko; A K Tikhaze; V V Kukharchuk; Yu N Belenkov |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bulletin of experimental biology and medicine Volume: 144 ISSN: 0007-4888 ISO Abbreviation: Bull. Exp. Biol. Med. Publication Date: 2007 Nov |
Date Detail:
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Created Date: 2008-08-07 Completed Date: 2008-12-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372557 Medline TA: Bull Exp Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 664-6 Citation Subset: IM |
Affiliation:
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A. L. Myasnikov Institute of Cardiology, Russian Cardiological Center, Russian Ministry of Health, Moscow. akam67@rambler.tu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angioplasty, Transluminal, Percutaneous Coronary / methods* Antioxidants / administration & dosage, therapeutic use Combined Modality Therapy Coronary Angiography Coronary Disease / metabolism, radiography, therapy* Coronary Stenosis / metabolism, radiography, therapy Free Radicals / metabolism* Glutathione Peroxidase / metabolism Humans Lipid Peroxidation / drug effects Male Middle Aged Probucol / administration & dosage, therapeutic use Time Factors Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Free Radicals; 23288-49-5/Probucol; EC 1.11.1.9/Glutathione Peroxidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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