Document Detail

Relationship between exercise tolerance, hemodynamics at rest and during exercise and ejection fraction, and their prognostic relevance in asymptomatic postinfarction patients.
MedLine Citation:
PMID:  8149387     Owner:  NLM     Status:  MEDLINE    
In 309 postmyocardial infarction patients (age 40 +/- 7.7 years) without persistent ischemia there is only a weak correlation between ejection fraction (EF) and exercise tolerance (r = 0.45, p < 0.01), and between EF and maximum cardiac output (CO; r = 0.41, p < 0.01) and maximum pulmonary capillary wedge pressure (PCWP; r = -0.32, p < 0.001). The same was true for exercise tolerance and maximum PCWP (r = -0.53, p < 0.001). A big scattering of individual values could be observed. Although we found a high positive correlation between maximum CO and exercise tolerance (r = 0.80, p < 0.001), in individual cases a low CO could be related to high exercise tolerance and vice versa. In the multivariate analysis, only the heart volume/kg body weight and maximum PCWP could be shown to be of independent prognostic importance for survival and/or mortality in the following years (chi 2 = 5.9, p < 0.015 and chi 2 = 7.2, p < 0.007, respectively).
K Meyer; L Samek; R E Sierra-Chavez; P Betz; K Schnellbacher; H Roskamm
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology     Volume:  84     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1994  
Date Detail:
Created Date:  1994-05-06     Completed Date:  1994-05-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  33-41     Citation Subset:  IM    
Rehabilitationszentrum für Herz- und Kreislaufkranke, Bad Krozingen, FRG.
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MeSH Terms
Cardiac Output / physiology*
Cardiac Volume / physiology
Exercise Test*
Follow-Up Studies
Hemodynamics / physiology*
Middle Aged
Myocardial Infarction / mortality,  physiopathology*
Retrospective Studies
Survival Rate
Ventricular Function, Left / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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