Document Detail

Relationship between enlargement of the lateral ventricle and periventricular leukomalacia in infants.
MedLine Citation:
PMID:  21058436     Owner:  NLM     Status:  MEDLINE    
AIM: To examine if we could predict periventricular leukomalacia (PVL) from the area of the lateral ventricle (LV).
METHODS: Six neonates in whom cystic PVL could be detected by magnetic resonance imaging (MRI) but not by ultrasound (US) were termed the 'invisible group'. Six neonates in whom cystic PVL could be detected by MRI and US were termed the 'visible group'. Eleven neonates in whom cystic PVL could not be detected by MRI or US were termed the 'control group'. The ratio of LV to head circumference (HC) was calculated as the area of LV (cm²)/HC (cm) × 100. Receiver operating characteristic (ROC) curve analysis was carried out to find the cutoff value.
RESULT: There were no significant differences among the three groups with respect to gestational age, birthweight, postnatal age and HC. The ratio of LV to HC in the control group was a median value of 0.38, it was 0.79 in the invisible group, and 0.96 in the visible group. The ratio was significantly higher in the visible group (P < 0.001) and in the invisible group (P < 0.05) than in the control group. This ratio was low in the two infants who had PVL only in the collateral trigone. The ROC curve suggested a cutoff value of 0.6 (sensitivity 79.17%, specificity 100%) to suspect PVL.
CONCLUSION: We may need to suspect PVL in infants whose lateral ventricle is enlarged even if cystic PVL is not detected by ultrasound. PVL present only in the collateral trigone needs to be evaluated using cerebral MRI.
Akihiko Kato; Satoshi Ibara; Yuko Maruyama; Masahito Terahara
Related Documents :
17466686 - Does peripartum infection increase the incidence of cerebral palsy in extremely low bir...
12427516 - Cerebral hemodynamics during early neonatal period in preterm infants with periventricu...
10789926 - Thrombosis of the deep cerebral veins with excessive bilateral infarction in a prematur...
8092866 - Factors affecting survival and outcome at 3 years in extremely preterm infants.
1408446 - Perinatal hip assessment in very low birth weight infants.
575696 - Association of handedness and birth order in monozygotic twins.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  36     ISSN:  1447-0756     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-11-05     Completed Date:  2011-02-11     Revised Date:  2012-01-19    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  984-90     Citation Subset:  IM    
Perinatal Center, Imakiire General Hospital, Kagoshima, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Analysis of Variance
Infant, Newborn
Lateral Ventricles / pathology*,  ultrasonography
Leukomalacia, Periventricular / pathology*,  ultrasonography
Magnetic Resonance Imaging
ROC Curve

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Correlations between the detection of stress-associated hormone/oxidative stress markers in umbilica...
Next Document:  The impact of systematic para-aortic and pelvic lymphadenectomy on survival in patients with optimal...