Document Detail


Relationship between endothelial dysfunction and nocturia with benign prostatic hyperplasia.
MedLine Citation:
PMID:  23323759     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective. There are limited data on whether there is an association between nocturia, benign prostatic hyperplasia (BPH) and endothelial dysfunction. The aim of the present study was to evaluate whether there is an association between nocturia and endothelial dysfunction in patients with BPH. Material and methods. Forty-two men with a diagnosis of BPH and 42 age-matched controls were enrolled. All patients were assessed for frequency and duration of nocturia, and prostate volume, completed the International Prostate Symptom Score (IPSS) questionnaire, and underwent brachial flow-mediated dilatation (FMD) evaluation. Results. There was a negative correlation between FMD and frequency of nocturia (r = -0.879, p < 0.0001). Moreover, there was a negative correlation between duration of nocturia and FMD (r = -0.890, p < 0.0001). In addition, FMD was significantly decreased in the BPH group compared with the control group (6.0 ± 0.09 to 7.8 ± 0.10%) (p = 0.0001). Conclusion. In patients with BPH, nocturia is associated with endothelial dysfunction and may be an insidious risk factor for cardiovascular disease.
Authors:
Mehmet Inci; Bahadir Sarli; Mursel Davarci; Fatih Rustu Yalcinkaya; Murat Mehmet Rifaioğlu; Ramazan Davran; Secil Arica; Sedat Motor; Onur Demirbaş
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-17
Journal Detail:
Title:  Scandinavian journal of urology     Volume:  -     ISSN:  2168-1813     ISO Abbreviation:  Scand J Urol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101587186     Medline TA:  Scand J Urol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Urology, Mustafa Kemal University School of Medicine, Hatay, Turkey.
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