Document Detail

Relationship between endometrial and subendometrial blood flow measured by three-dimensional power Doppler ultrasound and pregnancy after intrauterine insemination.
MedLine Citation:
PMID:  19463992     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate whether endometrial and subendometrial blood flow parameters measured using three-dimensional power Doppler ultrasound (3D PD-US) can predict pregnancy after IUI. DESIGN: Prospective clinical study. SETTING: Infertility center in a referral hospital. PATIENT(S): One hundred six women who underwent ovulation induction and IUI. INTERVENTION(S): A color Doppler ultrasound and a 3D PD-US examination were performed on the day of IUI. MAIN OUTCOME MEASURE(S): Pulsatility index (PI), resistance index (RI), and systolic/diastolic (S/D) ratio of uterine artery, and vascularization index (VI), flow index (FI), and vascularization flow index (VFI) of the endometrium as well as those of subendometrial region. These measurements were analyzed in relation to IUI outcome (pregnant vs. nonpregnant). RESULT(S): The pregnant group had higher endometrium VI, FI, and VFI scores than the nonpregnant group. In contrast, the subendometrial region VI, FI, and VFI scores did not differ between the groups, nor did the uterine artery PI, RI, and S/D. Pregnancies did not occur when endometrial blood flow had not been detected. CONCLUSION(S): Three-dimensional PD-US was useful for evaluating endometrial and subendometrial neovascularization in IUI cycles. Endometrial blood flow parameters may be useful predictors for pregnancy.
Ari Kim; Ji Eun Han; Tae Ki Yoon; Sang Woo Lyu; Hyun Ha Seok; Hyung Jae Won
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-05-22
Journal Detail:
Title:  Fertility and sterility     Volume:  94     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-07-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  747-52     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Department of Obstetrics and Gynecology and Fertility Center, CHA Gangnam Medical Center, CHA University, Seoul, South Korea.
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MeSH Terms
Blood Pressure
Endometrium / blood supply*,  ultrasonography*
Imaging, Three-Dimensional / methods*
Insemination, Artificial*
Neovascularization, Physiologic
Ovulation Induction
Predictive Value of Tests
Pregnancy Outcome
Prospective Studies
Pulsatile Flow
Regional Blood Flow
Ultrasonography, Doppler / methods*
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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