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Relationship between drinking patterns and the risk of type 2 diabetes: the Kansai Healthcare Study.
MedLine Citation:
PMID:  21131305     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background Moderate alcohol consumption is associated with a decreased risk of type 2 diabetes. However, the relationship between drinking patterns, such as the weekly frequency of alcohol consumption and the quantity per drinking day, and the incidence of type 2 diabetes has not been sufficiently addressed. Methods Study participants included 10 631 Japanese men aged 40-55 years without type 2 diabetes at entry. Type 2 diabetes was diagnosed if a fasting plasma glucose level was ≥7.0 mmol/l or if participants were taking diabetes medications. Data on alcohol consumption were obtained from questionnaires. Results During the 37 172 person-years of follow-up, we confirmed 878 cases of type 2 diabetes. Frequent alcohol consumption was associated with a low risk of type 2 diabetes. Compared to non-drinkers, the multiple-adjusted HR for those who drank 4-7 days weekly was 0.76 (95% CI, 0.63 to 0.92). To assess the association between drinking pattern and type 2 diabetes, we examined the joint association of the weekly frequency and the quantity per drinking day with type 2 diabetes. Men who consumed 0.1-2.0 or 2.1-4.0 US standard drinks per drinking day on 4-7 days weekly had a lower risk of type 2 diabetes (HR 0.74, 95% CI 0.58 to 0.95; HR 0.74, 95% CI 0.60 to 0.91, respectively) compared to non-drinkers. Conclusions More frequent alcohol consumption lowered the risk of type 2 diabetes. Light to moderate alcohol consumption per drinking day on 4-7 days weekly lowered the risk of type 2 diabetes compared to non-drinkers.
Authors:
Kyoko Kogawa Sato; Tomoshige Hayashi; Nobuko Harita; Hideo Koh; Isseki Maeda; Ginji Endo; Yoshiko Nakamura; Hiroshi Kambe; Chiharu Kiyotaki
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Publication Detail:
Type:  Journal Article     Date:  2010-12-03
Journal Detail:
Title:  Journal of epidemiology and community health     Volume:  66     ISSN:  1470-2738     ISO Abbreviation:  J Epidemiol Community Health     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909766     Medline TA:  J Epidemiol Community Health     Country:  England    
Other Details:
Languages:  eng     Pagination:  507-11     Citation Subset:  IM    
Affiliation:
Department of Preventive Medicine and Environmental Health, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan; ksato@med.osaka-cu.ac.jp.
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