| Relationship between directly measured portal pressure gradient and variceal hemorrhage. | |
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MedLine Citation:
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PMID: 7485008 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: It is commonly believed that variceal hemorrhage in patients with cirrhosis and portal hypertension does not occur below a portal pressure gradient (PPG) of 12 mm Hg. The aim of this study was to assess the relationship between directly measured portal pressure gradient and variceal hemorrhage. METHODS: The procedure of insertion of the transjugular intrahepatic portosystemic stent-shunt (TIPSS) for variceal hemorrhage provides access to the portal vein and allows direct measurement of the portal pressure. Right atrial, inferior vena caval, and portal pressure were recorded, and the PPG was calculated (portal pressure-inferior vena caval pressure) in 48 patients undergoing TIPSS for variceal hemorrhage. RESULTS: PPG was reduced from a mean of 21.4 (6.4) before TIPSS to 10.6 (3.1) mm Hg after the procedure. Seven patients (14.7%) had a baseline portal pressure gradient of < 12 mm Hg. CONCLUSION: The results of this study do not support the concept of a discrete bleeding threshold. |
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Authors:
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R Jalan; D N Redhead; E H Forrest; P C Hayes |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of gastroenterology Volume: 90 ISSN: 0002-9270 ISO Abbreviation: Am. J. Gastroenterol. Publication Date: 1995 Nov |
Date Detail:
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Created Date: 1995-12-08 Completed Date: 1995-12-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0421030 Medline TA: Am J Gastroenterol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1994-6 Citation Subset: IM |
Affiliation:
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Department of Medicine, Royal Infirmary of Edinburgh, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Atrial Function, Right
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physiology Esophageal and Gastric Varices / etiology, physiopathology*, surgery Female Gastrointestinal Hemorrhage / etiology, physiopathology*, surgery Humans Liver Cirrhosis / complications Liver Cirrhosis, Alcoholic / complications Male Middle Aged Portal Pressure / physiology* Portasystemic Shunt, Surgical / methods Stents Vena Cava, Inferior / physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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