Document Detail

Relationship between diet and blood pressure in a representative Mediterranean population.
MedLine Citation:
PMID:  12242584     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Hypertension is strongly associated with cardiovascular and renal disease. However, despite the efforts made to control hypertension via drug treatment, prevalence of controlled hypertension could be considered low. AIM OF THE STUDY: We performed the present study to investigate dietary habits among groups with different blood pressure status (normotensive, non-medicated hypertensive, medicated hypertensive) and to analyze the association between blood pressure and intakes of selected nutrients in normotensive and non-medicated hypertensive subjects (n = 1357), and furthermore in those undergoing hypertension drug treatment (n = 210; controlled and non-controlled). METHODS: The present cross-sectional, population-based survey (Gerona, Spain) included cardiovascular risk measurements and analysis of dietary intake with corresponding questionnaires. RESULTS: Nutrient intake was similar among groups of different blood pressure status after adjusting for sex, age and energy consumption. Multiple linear regression analysis, after adjustment for several confounders, showed that dietary intake of sodium was directly related to blood pressure. The same was seen for the sodium to potassium ratio and both were independent of hypertension drug treatment. In contrast, an inverse association was observed between blood pressure and dietary calcium intake. Moderate sodium (< 2400 mg Na/d) intake reduced the risk of hypertension by 30 % and 52 % (Odds ratio 0.70; 95 % CI 0.52-0.94, respectively) in normotensive and non-medicated hypertensive subjects. Furthermore, moderate sodium in combination with a calcium intake of more than 800 mg/d reduced the risk of inadequate blood pressure control, by 52 % (Odds ratio 0.48; 95 % CI 0.24-0.95) in subjects undergoing hypertension drug treatment. Controlled hypertension subjects have a significantly higher calcium intake than non-controlled. CONCLUSION: These results emphasize the importance of diet and overall of sodium intake as non-pharmacological approach in the prevention and treatment of hypertension.
H Schröder; E Schmelz; J Marrugat
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of nutrition     Volume:  41     ISSN:  1436-6207     ISO Abbreviation:  Eur J Nutr     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-09-20     Completed Date:  2002-12-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100888704     Medline TA:  Eur J Nutr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  161-7     Citation Subset:  IM    
Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d'Investigació Mèdicca, Barcelona, Spain.
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MeSH Terms
Blood Pressure*
Calcium, Dietary / administration & dosage
Cross-Sectional Studies
Energy Intake
Hypertension / epidemiology*,  prevention & control
Linear Models
Middle Aged
Odds Ratio
Risk Factors
Sodium, Dietary / administration & dosage
Spain / epidemiology
Reg. No./Substance:
0/Calcium, Dietary; 0/Sodium, Dietary

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