Document Detail

Relationship between collateral circulation and successful myocardial reperfusion in acute myocardial infarction: a subanalysis of the PREMIAR trial.
MedLine Citation:
PMID:  18388082     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to determine whether the presence of collateral circulation had a beneficial effect following primary angioplasty. In all, 114 patients who underwent primary angioplasty were included. Patients with collateral circulation had lower basal ST-segment deviation (P = .004), white cell count ( P = .001), peak creatine kinase (P = .001), and regional wall motion score values (P = .03) than patients without collateral circulation. After the procedure, the group with collaterals was associated with higher rates of normal myocardial blush, complete ST resolution, and shorter time to stable ST-recovery. Multivariable logistic analysis identified the presence of collateral circulation as independent predictor of normal myocardial blush (adjusted odds ratio = 3.98, 95% confidence interval, 1.12-14.09; P = .033) and rapid reperfusion (time to stable ST-segment recovery <7 minutes, adjusted odds ratio = 4.0, 95% confidence interval, 1.57-10.20; P = .004). The presence of collateral circulation has a protective effect on infarct size, resulting in faster reperfusion.
Mariano Albertal; Fernando Cura; Alejandro G Escudero; Lucio T Padilla; Jorge Thierer; Marcelo Trivi; Jorge A Belardi;
Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial     Date:  2008-04-02
Journal Detail:
Title:  Angiology     Volume:  59     ISSN:  1940-1574     ISO Abbreviation:  Angiology     Publication Date:    2008 Oct-Nov
Date Detail:
Created Date:  2008-10-21     Completed Date:  2008-11-04     Revised Date:  2010-09-14    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  587-92     Citation Subset:  IM    
Department of Interventional Cardiology, Instituto Cardiovascular de Buenos Aires, Argentina.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Collateral Circulation*
Coronary Angiography
Creatine Kinase / blood
Leukocyte Count
Middle Aged
Multivariate Analysis
Myocardial Infarction / therapy*
Recovery of Function
Reg. No./Substance:
EC Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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