Document Detail

Relationship between changes in power spectra of electroencephalograms and arterial halothane concentration in infants.
MedLine Citation:
PMID:  2511729     Owner:  NLM     Status:  MEDLINE    
A power spectral analysis of electroencephalograms (EEGs) was performed in 30 infants who underwent plastic surgery for cleft lip or cleft palate. The study was conducted to investigate whether there was a significant correlation between EEG changes and arterial halothane concentration in infants. The power spectral analysis of EEGs was performed by the fast Fourier transform (FFT). Arterial halothane concentration was measured with gas chromatography. The relationship between the changes in the power spectra of EEGs and the arterial halothane concentration was examined by means of a multivariate analysis. Prior to administration of halothane, two kinds of EEG patterns were discernible. In one pattern the peak of the EEG power spectra was seen in the slow wave band (slow wave group); in the other the peak of the power spectra was present in the fast wave band (fast wave group). In the occipital lead the multiple correlation coefficient and the index of determination of the slow wave group were 0.71 and 0.50, respectively, and those of the fast wave group were 0.78 and 0.61, respectively. A significant correlation was proved to be present between the normalized values of the EEG power spectra and arterial halothane concentration in the occipital lead. Therefore, the results of the present study suggest that the relationship between changes in the power spectra of EEGs in the occipital lead and arterial halothane concentration in infants can be expressed by means of multiple regression formulas.
K Sugiyama; S Joh; Y Hirota; Y Kiyomitsu; T Shibutani; H Niwa; H Matsuura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  33     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1990-01-05     Completed Date:  1990-01-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  670-5     Citation Subset:  IM    
Department of Dental Anesthesiology, Osaka University Faculty of Dentistry, Japan.
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MeSH Terms
Anesthesia, Inhalation*
Carbon Dioxide / analysis
Child, Preschool
Chromatography, Gas
Cleft Lip / surgery
Cleft Palate / surgery
Electroencephalography* / drug effects,  methods,  statistics & numerical data
Halothane / blood*
Multivariate Analysis
Respiratory Transport
Time Factors
Reg. No./Substance:
124-38-9/Carbon Dioxide; 151-67-7/Halothane

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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