| Relationship between cerebroplacental Doppler ratio and birth weight in postdates pregnancies. | |
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MedLine Citation:
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PMID: 15717288 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To explore the relationship between cerebroplacental Doppler impedance index and birth weight in postdates pregnancies, and to evaluate the use of a combination of Doppler parameters and ultrasound biometry in the prediction of large-for-gestational age (LGA) fetuses at 41 weeks of gestation. METHODS: The pulsatility indices of the umbilical (UA-PI) and middle cerebral (MCA-PI) arteries, the cerebroplacental pulsatility index ratio (CPR) and the estimated fetal weight (EFW) were obtained in a cohort of 181 ultrasound-dated pregnancies at 41 weeks' gestation, 2 days before induction of delivery. A regression equation was established and the correlation between umbilical artery impedance and different birth-weight centile groups was determined. A receiver-operating characteristics (ROC) curve was used to compare prediction of LGA fetuses using biometry alone with that using biometry and UA-PI. RESULTS: UA-PI was inversely related to EFW (Spearson's correlation coefficient rho = -0.28, P < 0.001). Logistic regression showed an independent contribution of UA-PI to the birth-weight estimation (birth weight = 1356.8 - 232.0 x UA-PI + 0.65 x EFW). On ROC curve analysis, the prediction of LGA with the regression equation was comparable to that using ultrasound biometry alone. CONCLUSION: UA-PI was inversely correlated to EFW, but the combination of ultrasound biometry and UA-PI compared with biometry alone showed similar prediction of LGA fetuses in postdates pregnancies. Further prospective trials on larger populations or groups with a higher prevalence of LGA fetuses would be needed to validate the use of the new formula. |
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Authors:
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H Lam; W C Leung; C P Lee; T T Lao |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology Volume: 25 ISSN: 0960-7692 ISO Abbreviation: Ultrasound Obstet Gynecol Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-03-03 Completed Date: 2005-06-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9108340 Medline TA: Ultrasound Obstet Gynecol Country: England |
Other Details:
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Languages: eng Pagination: 265-9 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, University of Hong Kong, HKSAR, China. lamswh@yahoo.com.hk |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Birth Weight Female Fetal Macrosomia / ultrasonography* Humans Infant, Newborn Infant, Postmature* Middle Cerebral Artery / ultrasonography* Pregnancy Pulsatile Flow ROC Curve Regression Analysis Sensitivity and Specificity Statistics, Nonparametric Ultrasonography, Doppler* Ultrasonography, Prenatal* Umbilical Arteries / ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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