Document Detail

Relationship between blood pressure levels and adherence to medication in patients with chronic heart failure: how come?
MedLine Citation:
PMID:  19436649     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate whether change in objective signs during up-titration of angiotensin-converting enzyme (ACE)-inhibitors in patients with chronic heart failure affect perception of information about medicines and subjective activities such as self-care.
METHODS: Consecutive patients referred for up-titration of ACE-inhibitors were included. Patients were given the Satisfaction with Information about Medicines Scale and the European Heart Failure Self-Care Behaviour Scale at their first visit and when the target dose was reached. Blood pressure, pulse and s-creatinine were measured at each visit.
RESULTS: Relationships were found between change in systolic (r = 0.224, p = 0.044) and diastolic (r = 0.361, p = 0.001) blood pressure and change in self-care scores and were also observed at baseline (r = 0.324, 0.398, p = 0.001, 0.000) and follow-up (r = 0.317, 0.253, p = 0.004, 0.022). Diastolic blood pressure correlated with the "potential problem of medication" score (r= -0.263, p = 0.007).
CONCLUSION: Patients with a more advanced disease usually have a lower blood pressure. Hence, the relationship between blood pressure and self-care scores might indicate that patients are more motivated to adhere to prescriptions the more advanced the stage of their disease.
Mahsa Mohammadi; Inger Ekman; Maria Schaufelberger
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Publication Detail:
Type:  Journal Article     Date:  2009-04-08
Journal Detail:
Title:  Vascular health and risk management     Volume:  5     ISSN:  1178-2048     ISO Abbreviation:  Vasc Health Risk Manag     Publication Date:  2009  
Date Detail:
Created Date:  2009-05-13     Completed Date:  2009-06-19     Revised Date:  2013-06-02    
Medline Journal Info:
Nlm Unique ID:  101273479     Medline TA:  Vasc Health Risk Manag     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  13-9     Citation Subset:  IM    
Department of Medicine, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden.
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MeSH Terms
Aged, 80 and over
Angiotensin-Converting Enzyme Inhibitors / administration & dosage*
Blood Pressure / drug effects*
Cardiovascular Agents / administration & dosage*
Chronic Disease
Drug Therapy, Combination
Health Knowledge, Attitudes, Practice
Heart Failure / drug therapy*,  physiopathology
Medication Adherence*
Middle Aged
Patient Satisfaction
Self Care
Severity of Illness Index
Treatment Outcome
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Cardiovascular Agents

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