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Relationship between asthma and cognition: the Cooper Center Longitudinal Study.
MedLine Citation:
PMID:  23409872     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Minimal data are available on the relationship between asthma and cognitive performance. In this report, we examine the relationship between asthma and cognitive performance in older adults, a subpopulation with elevated risk of cognitive impairment. METHODS: We conducted a cross-sectional, retrospective analysis of 1380 participants age ≥55 who completed preventive health examinations at the Cooper Clinic in Dallas, TX. Cognition was assessed using the Montreal Cognitive Assessment (MoCA), a brief test for mild cognitive impairment. Data were analyzed in a multiple logistic regression using MoCA scores suggestive of cognitive impairment as the dependent variable. RESULTS: When controlling for demographic characteristics, self-rated health status, inhaled corticosteroid use, and FEV(1) /FVC, asthma were associated with 78% increased risk of cognitive impairment (P = 0.02) as defined by MoCA score. CONCLUSIONS: In the largest sample examined to date, we have identified a significant relationship between asthma and cognitive impairment in older people.
Authors:
G Caldera-Alvarado; D A Khan; L F Defina; A Pieper; E S Brown
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-15
Journal Detail:
Title:  Allergy     Volume:  -     ISSN:  1398-9995     ISO Abbreviation:  Allergy     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804028     Medline TA:  Allergy     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.
Affiliation:
Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas.
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