Document Detail

Relationship between angiographically documented coronary artery disease and low bone mass in men.
MedLine Citation:
PMID:  17587717     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The present study aimed to investigate the association between low bone mass (LBM) and coronary artery disease (CAD) in male patients. METHOD AND RESULTS: The data for 47 men who were screened for osteopenia and osteoporosis with dual energy X-ray absorptiometry and then underwent coronary angiography between February 2005 and May 2006 were retrospectively analyzed. Bone mineral density of the femur neck was stratified as normal (T score >-1.0 SD) or low (T score <-1.0 SD) and CAD was defined as > or = 50% occlusion in at least 1 major coronary artery. Thirty-two patients were found to have angiographically significant CAD. Patients in the LBM group had a significantly higher incidence of CAD. Low bone mass was significantly and positively correlated with the Gensini scores of the patients (r=0.6037, p<0.0001) and was found to be an independent predictor of CAD in multivariate logistic regression analysis (odds ratio: 5.4 [95% confidence interval 1.66 and 17.49]; p=0.0049). Repeated statistical analyses with the acceptance of CAD as coronary artery stenosis >75% confirmed the same results. CONCLUSION: Low bone mass was significantly associated with angiographically documented CAD in males.
Enver Erbilen; Selma Yazici; Hakan Ozhan; Serkan Bulur; Serkan Ordu; Mehmet Yazici
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  71     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-06-25     Completed Date:  2007-08-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1095-8     Citation Subset:  IM    
Department of Cardiology, Düzce University, Düzce, Turkey.
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MeSH Terms
Absorptiometry, Photon
Bone Density / physiology*
Bone Diseases, Metabolic / complications*,  diagnosis,  physiopathology
Coronary Angiography
Coronary Artery Disease / complications*,  diagnosis,  physiopathology*
Cross-Sectional Studies
Femur Neck / physiopathology
Logistic Models
Middle Aged
Odds Ratio
Osteoporosis / complications*,  diagnosis,  physiopathology
Predictive Value of Tests
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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