| Relationship between angiographically documented coronary artery disease and low bone mass in men. | |
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MedLine Citation:
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PMID: 17587717 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The present study aimed to investigate the association between low bone mass (LBM) and coronary artery disease (CAD) in male patients. METHOD AND RESULTS: The data for 47 men who were screened for osteopenia and osteoporosis with dual energy X-ray absorptiometry and then underwent coronary angiography between February 2005 and May 2006 were retrospectively analyzed. Bone mineral density of the femur neck was stratified as normal (T score >-1.0 SD) or low (T score <-1.0 SD) and CAD was defined as > or = 50% occlusion in at least 1 major coronary artery. Thirty-two patients were found to have angiographically significant CAD. Patients in the LBM group had a significantly higher incidence of CAD. Low bone mass was significantly and positively correlated with the Gensini scores of the patients (r=0.6037, p<0.0001) and was found to be an independent predictor of CAD in multivariate logistic regression analysis (odds ratio: 5.4 [95% confidence interval 1.66 and 17.49]; p=0.0049). Repeated statistical analyses with the acceptance of CAD as coronary artery stenosis >75% confirmed the same results. CONCLUSION: Low bone mass was significantly associated with angiographically documented CAD in males. |
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Authors:
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Enver Erbilen; Selma Yazici; Hakan Ozhan; Serkan Bulur; Serkan Ordu; Mehmet Yazici |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 71 ISSN: 1346-9843 ISO Abbreviation: Circ. J. Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-06-25 Completed Date: 2007-08-21 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 1095-8 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Düzce University, Düzce, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Absorptiometry, Photon Aged Bone Density / physiology* Bone Diseases, Metabolic / complications*, diagnosis, physiopathology Coronary Angiography Coronary Artery Disease / complications*, diagnosis, physiopathology* Cross-Sectional Studies Femur Neck / physiopathology Humans Logistic Models Male Middle Aged Odds Ratio Osteoporosis / complications*, diagnosis, physiopathology Predictive Value of Tests Retrospective Studies Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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