| Relationship between alcohol habits and hemorheology by a micro channel method in a general population. | |
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MedLine Citation:
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PMID: 18855354 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Hemorheology plays an important role in the development of cardiovascular disease. The Micro Channel array Flow Analyzer (MC-FAN) (Hitachi Haramachi Electronics Co., Ltd., Bentencho, Japan) is currently considered a useful new device to analyze hemorheology. However, the relationships between various lifestyle habits and hemorheology, especially using MC-FAN, have still not been thoroughly investigated. HYPOTHESIS: The study was undertaken to determine whether there could be some correlations of lifestyle factors to hemorheology by MC-FAN. METHODS: A total of 250 asymptomatic Japanese subjects (male:female = 100:150; mean age = 49.7 y) without any medication were enrolled in the present study. Hemorheology was assessed by the whole blood passage time (WBPT) and was corrected by the saline passage time using MC-FAN. Subjects' lifestyle factors, such as smoking habits, alcohol habits, and physical activity, were self-reported. RESULTS: Partial correlation analysis for WBPT, after controlling for age, gender, hematocrit, white blood cell count, body mass index, blood pressure, blood biochemical measures, and all lifestyle habits, revealed a significant and inverse correlation between alcohol habits of 1-3 go (amount of alcohol intake) and WBPT (r = - 0.191, p = 0.003), in addition to a significant positive correlation between serum low-density lipoprotein (LDL) cholesterol and WBPT. CONCLUSIONS: These data suggest that alcohol habits may beneficially affect hemorheology by MC-FAN, expanding the protective effect of light-to-moderate alcohol consumption against cardiovascular disease. |
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Authors:
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Kazuhiko Kotani; Seiji Adachi; Yoneatsu Osaki; Youichi Kurozawa; Shigeru Araga |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical cardiology Volume: 31 ISSN: 0160-9289 ISO Abbreviation: Clin Cardiol Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-10-21 Completed Date: 2009-01-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7903272 Medline TA: Clin Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 488-91 Citation Subset: IM |
Affiliation:
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Department of Social Medicine, Division of Health Administration and Promotion, Yonago, Japan. kakotani@grape.med.torttori-u.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alcohol Drinking
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blood*,
epidemiology Cardiovascular Diseases / blood, epidemiology, prevention & control* Female Follow-Up Studies Hematologic Tests / methods Hemorheology / physiology* Humans Incidence Japan / epidemiology Leukocyte Count Lipoproteins, LDL / blood Male Middle Aged Prognosis Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Lipoproteins, LDL |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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