Document Detail

Relationship between Venous and Arterial Thrombosis: A Review of the Literature from a Causal Perspective.
MedLine Citation:
PMID:  22198853     Owner:  NLM     Status:  In-Data-Review    
Venous thrombosis and arterial thrombosis are traditionally regarded as two different diseases with respect to pathophysiology, epidemiology, and treatment strategies. Research findings of the past few years suggest that this categorical distinction may be too strict. However, whether the described relationship between venous and arterial thrombosis is real or a result of other factors such as confounding, chance, or bias is still unclear. In this review, we discuss the current literature while using causal diagrams to better understand possible causal relations between cardiovascular risk factors, atherosclerosis, arterial thrombosis, and venous thrombosis. Furthermore, we propose study designs to investigate the causal link between venous and arterial thrombosis. In addition, we comment on the effect of statin use on the occurrence of both arterial and venous thrombosis. The possible clinical implications of these findings are discussed.
Willem M Lijfering; Linda E Flinterman; Jan P Vandenbroucke; Frits R Rosendaal; Suzanne C Cannegieter
Related Documents :
3567453 - Experimental microarterial grafts: freeze-dried heterografts versus autografts.
11904803 - Percutaneous endovascular abdominal aortic aneurysm repair.
3213433 - Allometry of the perivascular spaces of the putamen in aging.
Publication Detail:
Type:  Journal Article     Date:  2011-12-23
Journal Detail:
Title:  Seminars in thrombosis and hemostasis     Volume:  37     ISSN:  1098-9064     ISO Abbreviation:  Semin. Thromb. Hemost.     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-12-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0431155     Medline TA:  Semin Thromb Hemost     Country:  United States    
Other Details:
Languages:  eng     Pagination:  885-96     Citation Subset:  IM    
Copyright Information:
© Thieme Medical Publishers.
Department of Clinical Epidemiology, Leiden University Medical Center, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Alcohol dosing and the heart: updating clinical evidence.
Next Document:  Dyslipidemia, statins, and venous thromboembolism.