| The Relationship between Plasma alpha-Tocopherol Concentration and Vitamin E Intake in Patients with Type 2 Diabetes Mellitus. | |
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MedLine Citation:
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PMID: 22002214 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Type 2 diabetes mellitus (DM2) predisposes to an increased production of free radicals and a probable reduction in plasma antioxidants, including vitamin E. This cross-sectional study investigated the relationship between plasma alpha-Tocopherol concentration and vitamin E intake in 58 Brazilians with DM2. Plasma alpha-Tocopherol was determined by high-performance liquid chromatography. The intake of vitamin E-rich foods was assessed by a food frequency questionnaire. Total cholesterol and fractions were measured by colorimetric enzymatic methods. Data on demographic and socioeconomic factors, life habits, and anthropometry were obtained by a questionnaire and physical examination. The association between plasma alpha-Tocopherol and vitamin E intake was assessed by multiple linear regression analysis. The following variables were included in the regression model: alpha-Tocopherol, vitamin E intake, total cholesterol and fractions, body mass index, waist circumference, gender, age, education, occupation, income, smoking, alcohol intake, and blood pressure. There was no association between alpha-Tocopherol and vitamin E intake, but there were significant associations between alpha-Tocopherol and total cholesterol (p < 0.001) and waist circumference (p = 0.003). There were 36.2 % diabetics with low alpha-Tocopherol concentrations (< 12 µmol/L) and 32.7 % with a low alpha-Tocopherol/total cholesterol ratio (< 2.2). Further large, epidemiological, longitudinal studies, including measurements of gamma-tocopherol in blood, should be conducted to confirm our results. |
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Authors:
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Vanessa K Illison; Patricia H C Rondó; Andréia M de Oliveira; Francisco H D Abronzo; Katia F Campos |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition Volume: 81 ISSN: 0300-9831 ISO Abbreviation: Int J Vitam Nutr Res Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-10-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1273304 Medline TA: Int J Vitam Nutr Res Country: Switzerland |
Other Details:
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Languages: eng Pagination: 12-20 Citation Subset: IM |
Affiliation:
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Nutrition Department, School of Public Health, University of São Paulo, Brasil. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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