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Relationship between P-wave duration and atrial electromechanical delay assessed by tissue Doppler echocardiography.
MedLine Citation:
PMID:  21029132     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: The aim of the study was to assess the relationship between P-wave duration on the surface electrocardiogram (ECG) and echocardiographic parameters of atrial electromechanical delay (EMD), as well as contraction synchrony during different atrial pacing modalities.
METHODS: In 57 patients with sinus node disease and prolonged sinus P-wave duration treated with multisite atrial pacing (MSAp), the EMD was measured by tissue Doppler in several left and right atrial sites during sinus rhythm, MSAp, and single-site pacing at right atrial appendage (RAAp), Bachmann's bundle (BBp) region, and coronary sinus (CSp) ostium. Regional atrial synchrony was calculated on the basis of EMD.
RESULTS: P-wave duration was 141 ± 16, 120 ± 17, 138 ± 17, 144 ± 16, and 160 ± 19 ms during sinus rhythm, MSAp, BBp, CSp, and RAAp, respectively (P < 0.001 RAAp and MSAp vs other). P-wave duration correlated with all atrial EMDs as well as interatrial and intraleft atrial parameters of dyssynchrony. In multivariate analysis, the EMD in lateral left atrial wall was the strongest predictor of P-wave duration (β 0.41; P < 0.001). The relationship between P-wave duration and the atrial EMDs was most prominent during RAAp (all left atrial walls r > 0.51; P < 0.01) and BBp (all atrial walls r > 0.42; P < 0.05), while during sinus rhythm and CSp, only weak correlation between echo and ECG was found. Neither of the tissue Doppler parameters correlated with P-wave duration during MSAp. Interatrial dyssynchrony correlated with P-wave duration during sinus rhythm and RAAp and intraleft atrial dyssynchrony only during sinus rhythm.
CONCLUSIONS: P-wave duration of the surface ECG is highly correlated with the atrial EMD, the relationship is specific for each pacing modality.
Authors:
Alicja Dąbrowska-Kugacka; Ewa Lewicka-Nowak; Piotr Ruciński; Paweł Zagożdżon; Grzegorz Raczak; Andrzej Kutarski
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-10-28
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  34     ISSN:  1540-8159     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  23-31     Citation Subset:  IM    
Copyright Information:
©2010, The Authors. Journal compilation ©2010 Wiley Periodicals, Inc.
Affiliation:
Department of Cardiology and Electrotherapy, Medical University of Gdańsk, Gdańsk, Poland. adabrowska@gumed.edu.pl
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