Document Detail


Relationship between Fc receptors and Ia alloantigens: analysis with a sensitive radioimmunoassay.
MedLine Citation:
PMID:  70064     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This paper describes the successful use of 125I-labeled CgG aggregate to detect Ia-type alloantibodies in pregnancy sera. The blockade of aggregate uptake of a variety of normal mononuclear and leukemic cell types by anti-Ia alloantibodies is analyzed. Fc receptors and Ia alloantigens are clearly two distinct moleculr entities. The association between Fc receptors and Ia alloantigens on a quantitative level seems to depend on a ligand-binding mechanism to control their interaction rather than the presence of a topographical molecular tandem arrangement.
Authors:
E P Rieber; P Wernet
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of immunology     Volume:  6     ISSN:  0300-9475     ISO Abbreviation:  Scand. J. Immunol.     Publication Date:  1977  
Date Detail:
Created Date:  1977-09-17     Completed Date:  1977-09-17     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0323767     Medline TA:  Scand J Immunol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  465-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Binding Sites
Binding, Competitive
Cell Membrane
Epitopes
Female
Humans
Immunoglobulin Fc Fragments*
Isoantigens*
Pregnancy
Radioimmunoassay
Chemical
Reg. No./Substance:
0/Epitopes; 0/Immunoglobulin Fc Fragments; 0/Isoantigens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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