Document Detail

The relationship of newborn adiposity to fetal growth outcome based on birth weight or the modified neonatal growth assessment score.
MedLine Citation:
PMID:  22494346     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: (1) Develop reference ranges of neonatal adiposity using air displacement plethysmography. (2) Use new reference ranges for neonatal adiposity to compare two different methods of evaluating neonatal nutritional status.
METHODS: Three hundred and twenty-four normal neonates (35-41 weeks post-menstrual age) had body fat (%BF) and total fat mass (FM, g) measured using air displacement plethysmography shortly after delivery. Results were stratified for 92 of these neonates with corresponding fetal biometry using two methods for classifying nutritional status: (1) population-based weight percentiles; and (2) a modified neonatal growth assessment score (m(3)NGAS(51)).
RESULTS: At the 50th percentile, %BF varied from 7.7% (35 weeks) to 11.8% (41 weeks), while the corresponding 50th percentiles for total FM were 186-436 g. Among the subset of 92 neonates, no significant differences in adiposity were found between small for gestational age (SGA), appropriate for gestational age (AGA), and large for gestational age (LGA) groups using population-based weight standards. Classification of the same neonates using m(3)NGAS(51) showed significant differences in mean %BF between corresponding groups.
CONCLUSIONS: Population-based weight criteria for neonatal nutritional status can lead to misclassifications on the basis of adiposity. A neonatal growth assessment score, that considers the growth potential of several anatomic parameters, appears to more effectively classify under- and over-nourished newborns.
Wesley Lee; Thomas Riggs; Winston Koo; Russell L Deter; Lami Yeo; Roberto Romero
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, N.I.H., Intramural     Date:  2012-05-29
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  25     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-18     Completed Date:  2013-03-17     Revised Date:  2014-02-24    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1933-40     Citation Subset:  IM    
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MeSH Terms
Birth Weight*
Cross-Sectional Studies
Diabetes, Gestational
Fetal Development*
Fetal Macrosomia / diagnosis*,  etiology
Infant, Newborn
Infant, Premature
Infant, Small for Gestational Age*
Linear Models
Nutrition Assessment*
Nutritional Status
Pregnancy in Diabetics
Prospective Studies
Reference Values
Ultrasonography, Prenatal
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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