| The relationship between visit-to-visit variability in systolic blood pressure and all-cause mortality in the general population: findings from NHANES III, 1988 to 1994. | |
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MedLine Citation:
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PMID: 21200000 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recent data suggest that visit-to-visit variability of blood pressure is associated with stroke incidence. Correlates of increased visit-to-visit variability in blood pressure and the relationship between variability and all-cause mortality were examined using data on US adults ≥ 20 years of age from the Third National Health and Nutrition Examination Survey (n = 956). Three consecutive blood pressure readings were taken during 3 separate study visits from 1988 to 1994. Based on the mean of the second and third measurements from each visit, visit-to-visit blood pressure variability for each participant was defined using the standard deviation and coefficient of variation across visits. Mortality was assessed through December 31, 2006 (median follow-up = 14 years; n = 240 deaths). The mean of the standard deviation for systolic blood pressure across visits was 7.7 mm Hg. After multivariable adjustment, older age, female gender, history of myocardial infarction, higher mean systolic blood pressure and pulse pressure, and use of angiotensin converting enzyme inhibitors were associated with higher standard deviation in systolic blood pressure. The multivariable adjusted hazard ratios for all-cause mortality associated with a standard deviation of systolic blood pressure of 4.80 to 8.34 mm Hg and ≥ 8.35 mm Hg, versus <4.80 mm Hg, were 1.57 (95% CI, 1.07 to 2.18) and 1.50 (95% CI, 1.03 to 2.18), respectively. Results were similar when coefficient of variation for systolic blood pressure was evaluated. Visit-to-visit variability for diastolic blood pressure was not associated with mortality. In this population-based study of US adults, higher levels of short-term visit-to-visit variability in systolic blood pressure were associated with increased all-cause mortality. |
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Authors:
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Paul Muntner; Daichi Shimbo; Marcello Tonelli; Kristi Reynolds; Donna K Arnett; Suzanne Oparil |
Publication Detail:
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Type: Journal Article Date: 2011-01-03 |
Journal Detail:
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Title: Hypertension Volume: 57 ISSN: 1524-4563 ISO Abbreviation: Hypertension Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-20 Completed Date: 2011-04-22 Revised Date: 2011-09-29 |
Medline Journal Info:
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Nlm Unique ID: 7906255 Medline TA: Hypertension Country: United States |
Other Details:
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Languages: eng Pagination: 160-6 Citation Subset: IM |
Affiliation:
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Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. pmuntner@uab.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angiotensin-Converting Enzyme Inhibitors / therapeutic use Blood Pressure / drug effects, physiology* Cause of Death Female Follow-Up Studies Health Surveys / statistics & numerical data Humans Hypertension / drug therapy, mortality, physiopathology* Linear Models Male Middle Aged Multivariate Analysis Office Visits* Proportional Hazards Models Risk Factors United States / epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Angiotensin-Converting Enzyme Inhibitors |
| Comments/Corrections | |
Comment In:
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Hypertension. 2011 Jul;58(1):e1; author reply e2
[PMID:
21576626
]
Hypertension. 2011 Sep;58(3):e16 [PMID: 21810654 ] Hypertension. 2011 Feb;57(2):141-3 [PMID: 21199992 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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