Document Detail

Relationship Between Melanoma Detection Pattern and Tumor Thickness.
MedLine Citation:
PMID:  25073734     Owner:  NLM     Status:  Publisher    
BACKGROUND: Melanoma tumor thickness remains the most important determinant of patient survival. Several large population-based studies have shown that full-body skin examinations (FBSE) improve melanoma mortality and others that FBSEs may detect melanomas at a thinner, more curable stage.
PURPOSE: To relate the detection method to lesion thickness at the time of diagnosis.
METHODS: A retrospective chart review of all cases of biopsy-proven primary cutaneous melanomas diagnosed from 2000 to 2012 at the Veterans Affairs Hospital in Brooklyn NY was conducted. Data were collected in 2012-2013 and analyzed in 2013. Main outcome measures include lesion thickness stratified by method of detection and probabilities of detecting thin lesions per method (using cut-offs of in situ and 0.75 mm). Secondary outcomes include interaction between method and body site or lesion diameter.
RESULTS: Sixty-three percent of melanomas were detected by FBSE and 59% of all melanomas were in situ. There was no statistically significant difference in thickness among the detection groups when a cut-off of in situ (Fisher's exact test, p=0.6148) or 0.75 mm was used (p=0.8910). A majority of lesions on the back were found by FBSE (68%).
CONCLUSIONS: FBSE was not shown to detect melanomas at a thinner stage. Prospective studies are needed to analyze the utility and efficacy of FBSEs in clinical practice.
Estee L Williams; Man Kin Derek Ho; Allan C Halpern; Orit Markowitz; Daniel M Siegel
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-7-26
Journal Detail:
Title:  American journal of preventive medicine     Volume:  -     ISSN:  1873-2607     ISO Abbreviation:  Am J Prev Med     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-7-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8704773     Medline TA:  Am J Prev Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 American Journal of Preventive Medicine. All rights reserved.
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