| Relationship between body mass index and mortality in adults on maintenance hemodialysis: a systematic review. | |
| | |
MedLine Citation:
|
PMID: 20580250 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The primary objective of this systematic review was to determine the relationship between body mass index (BMI) and all-cause and cardiovascular mortality. DESIGN: Systematic review of primarily observational studies. PATIENTS: Adult patients from all gender, race, or ethnic groups on maintenance hemodialysis. METHODS: Medline, Science Citation Index, Academic Search Premier, Cochrane Library, and Embase electronic databases covering the period 1966 to December 2008 were searched with the help of a qualified librarian. Reference lists of included papers and collections also were searched. Each study was reviewed by 2 independent reviewers who also performed the data extraction from full papers. Differences between reviewers were resolved by consensus or by a third reviewer in the case of disagreements. The quality of studies selected for inclusion in the systematic review was also assessed by 2 independent reviewers. MAIN OUTCOMES: BMI and mortality. RESULTS: Eighteen studies (60%) reported a significant inverse relationship between all-cause mortality and BMI. This inverse relationship was more prevalent in older patients, larger retrospective studies, and studies that did not adjust for inflammation. On the other hand, 57% of the 7 studies reporting on cardiovascular mortality found no significant relationship with BMI. CONCLUSIONS: This systematic review shows evidence of an inverse relationship between BMI and all-cause mortality in adult patients on maintenance HD, especially in older patients, but the relationship with cardiovascular mortality is less clear. |
| | |
Authors:
|
Marietjie Herselman; Nazeema Esau; Jean-Marie Kruger; Demetre Labadarios; Mohammed Rafique Moosa |
Publication Detail:
|
Type: Journal Article; Review Date: 2010-06-26 |
Journal Detail:
|
Title: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation Volume: 20 ISSN: 1532-8503 ISO Abbreviation: J Ren Nutr Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-23 Completed Date: 2010-12-14 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9112938 Medline TA: J Ren Nutr Country: United States |
Other Details:
|
Languages: eng Pagination: 281-292, 7 p following 292 Citation Subset: IM |
Copyright Information:
|
(c) 2010 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Division of Human Nutrition, Stellenbosch University, Tygerberg, South Africa. mgh@sun.ac.za |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Age Distribution Body Mass Index* Cardiovascular Diseases / complications, mortality* Cause of Death Humans Kidney Failure, Chronic / complications, mortality*, therapy Renal Dialysis* Retrospective Studies Risk Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The modulative effect of Cyperi Rhizoma on Th1/Th2 lineage development.
Next Document: The effect of resistance exercise to augment long-term benefits of intradialytic oral nutritional su...