Document Detail

Relations between nucleolar morphometric parameters and pre-rRNA synthesis in animal and plant cells.
MedLine Citation:
PMID:  3638905     Owner:  NLM     Status:  MEDLINE    
In order to study if there are differences between cells of the same tissue with one and two nucleoli, nuclear and nucleolar volume, density of tritiated uridine incorporation, amount of DNA per nucleus and intensity of cytoplasmic basophilia were measured in mononucleolated and binucleolated rat epithelial endometrial cells, in onion root meristematic cells and in chick embryo matrix cells of the central nervous system, neuroblasts and neurons. No significant differences in nuclear volume, density of tritiated uridine incorporation and amount of DNA per nucleus were found between cells of the same type with diverse numbers of nucleoli. Binucleolated endometrial cells, matrix cells, and root meristematic cells have biphasic distributions of nucleolar volumes. One peak of this distribution roughly coincides with the nucleolar volume of mononucleolated cells, the other peak corresponds almost to double the volume. As the density of uridine incorporation is the same irrespective of the nucleolar number and volume, the cells with larger nucleolar volumes have higher pre-rRNA synthesis. These cells also have higher amounts of ribosomes in the cytoplasm, as revealed by the photometric study of basophilia. It is concluded that in this population of cells the ribosomal production is regulated to a higher steady equilibrium than in the general population. This difference is not due to polyploidism or to the increased DNA content of G2 phase cells. Binucleolated neuroblasts and neurons have nucleolar volumes similar to those of mononucleolated ones.
G H Vázquez Nin; O M Echeverría; G Zavala; L F Jiménez-García; M A González; R Parra
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta anatomica     Volume:  126     ISSN:  0001-5180     ISO Abbreviation:  Acta Anat (Basel)     Publication Date:  1986  
Date Detail:
Created Date:  1986-10-16     Completed Date:  1986-10-16     Revised Date:  2007-07-02    
Medline Journal Info:
Nlm Unique ID:  0370272     Medline TA:  Acta Anat (Basel)     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  141-6     Citation Subset:  IM    
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MeSH Terms
Cell Nucleolus / ultrastructure*
Cell Nucleus / ultrastructure
Endometrium / metabolism,  ultrastructure
Epithelium / metabolism,  ultrastructure
Nucleic Acid Precursors / biosynthesis*
Plants / metabolism,  ultrastructure*
RNA Precursors
RNA, Ribosomal / biosynthesis*
Ribosomes / ultrastructure
Reg. No./Substance:
0/Nucleic Acid Precursors; 0/RNA Precursors; 0/RNA, Ribosomal

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