Document Detail


Relations between maternal and fetal plasma concentrations of placental lactogen and placental and fetal weights in well-fed ewes.
MedLine Citation:
PMID:  2061238     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The concentration of ovine placental lactogen (oPL) in maternal plasma varies with litter size and nutritional status, making it difficult to compare these concentrations across studies. In this study, 27 Dorset and Finn-Dorset crossbred ewes with litters of known size and gestational age were used to relate concentrations of oPL in maternal plasma to placental and fetal weights. Fetal oPL concentrations also were correlated to these variables in 12 chronically catheterized singleton fetuses. The concentration of oPL in maternal plasma increased with increasing placental weight across litter sizes ranging from 1 to 3 (r = .716). When expressed per gram of placenta, oPL was greater (P less than .05) in those ewes carrying multiple fetuses. There was no correlation between maternal and fetal oPL in time-matched samples or in average values between individuals for ewes carrying singleton pregnancies. Within the singleton group, placental weight and fetal weight were well correlated (r = .761), as were the concentration of fetal plasma oPL and fetal weight (r = .699). Placental weight plus fetal oPL could explain 81% of the variation seen in fetal weight. These results imply that maternal and fetal oPL release are controlled independently and that fetal oPL affects fetal growth by a mechanism not directly related to placental size.
Authors:
P A Schoknecht; S N Nobrega; J A Petterson; R A Ehrhardt; R Slepetis; A W Bell
Related Documents :
10463348 - Lack of correlation between placenta and offspring size in mouse interspecific crosses.
11237128 - Placentation, antiphospholipid syndrome and pregnancy outcome.
11440548 - Placental calcification: a metastatic process?
14706678 - Endothelin and the regulation of uterine and placental perfusion in hypoxia-induced fet...
23772768 - A case of successful pregnancy in a ewe with uterus didelphys.
17610438 - The impact of welfare reform on insurance coverage before pregnancy and the timing of p...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of animal science     Volume:  69     ISSN:  0021-8812     ISO Abbreviation:  J. Anim. Sci.     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-08-07     Completed Date:  1991-08-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8003002     Medline TA:  J Anim Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1059-63     Citation Subset:  IM    
Affiliation:
Department of Anim. Sci., Cornell University, Ithaca, NY 14853.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Embryonic and Fetal Development*
Female
Fetal Blood / chemistry
Gestational Age
Litter Size
Organ Size
Placenta / anatomy & histology*
Placental Lactogen / blood*
Pregnancy
Pregnancy, Animal / blood,  metabolism*
Regression Analysis
Sheep / blood,  metabolism*
Chemical
Reg. No./Substance:
9035-54-5/Placental Lactogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Wood chewing by stabled horses: diurnal pattern and effects of exercise.
Next Document:  Fatty acid elongation and desaturation enzyme activities of bovine liver and subcutaneous adipose ti...