Document Detail

Relation of spontaneous reperfusion in ST-elevation myocardial infarction to more distal coronary culprit narrowings.
MedLine Citation:
PMID:  18237590     Owner:  NLM     Status:  MEDLINE    
Spontaneous reperfusion (SR) of the infarct-related artery may occur in patients with ST-segment-elevation myocardial infarctions (STEMIs). Limited data are available on the angiographic characteristics of these patients. The objective of this study was to determine if there are differences in the distance of the culprit lesion from the coronary ostium in patients with STEMIs with and without SR. Patients who presented with acute STEMIs<12 hours after pain onset and who underwent coronary angiography were entered into the study. Measurement of the distance from the coronary ostium to the culprit lesion was performed. A total of 469 patients with STEMIs were included in the study, of whom 77 met criteria for SR (significant relief of chest pain associated with >or=50% resolution of ST-segment elevation on follow-up electrocardiography) and 392 did not. A highly significant difference was seen in ostial to culprit lesion distance, with the culprit lesions in the SR group being more distal than those in the non-SR group (45+/-22 vs 39+/-20 mm, p<0.009). In conclusion, the findings of this study demonstrate that the location of the culprit lesion in patients with STEMIs who undergo SR is more distal in the involved artery than in patients with STEMIs who do not undergo SR.
David Leibowitz; Penko Gerganski; Johannes Nowatzky; A Teddy Weiss; David Rott
Publication Detail:
Type:  Journal Article     Date:  2007-12-11
Journal Detail:
Title:  The American journal of cardiology     Volume:  101     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-01     Completed Date:  2008-03-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  308-10     Citation Subset:  AIM; IM    
Coronary Care Unit, Hadassah-Hebrew University Medical Center, Mount Scopus, Jerusalem, Israel.
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MeSH Terms
Coronary Vessels / pathology*
Creatine Kinase / blood
Middle Aged
Myocardial Infarction / blood,  pathology*
Remission, Spontaneous
Retrospective Studies
Reg. No./Substance:
EC Kinase

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